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Co doped ZnO thin films deposited by spin coating as antibacterial coating for metallic implants

机译:CO掺杂的ZnO薄膜通过旋涂沉积,作为金属植入物的抗菌涂层

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摘要

Pure and Co doped ZnO thin films were deposited on Ti substrates by spin coating and further thermally treated at 500 or 600 degrees C in order to achieve implantable metallic materials with improved biocompatibility and antibacterial effect. The influence of dopant concentration on the physical, chemical and biological characteristics was also approached, namely values of 0.5, 1.0, 1.5, 2.0 and 5.0 mol% Co. The coated structures were investigated in terms of composition, structure, morphology, wetting properties, antibacterial activity and biological response in the presence of amniotic fluid stem cells. The results proved that all deposited samples are nanostructured, with thicknesses below 1 mu m, show a very good antimicrobial effect and prove to be suitable supports for cellular adhesion and proliferation.
机译:通过旋涂在Ti基材上沉积纯和CO掺杂的ZnO薄膜,并在500或600℃下进一步热处理,以实现具有改善的生物相容性和抗菌作用的可植入金属材料。 掺杂剂浓度对物理,化学和生物学特性的影响也接近,即0.5,1.0,1.5,2.0和5.0mol%Co.的值在组成,结构,形态,润湿性能方面研究了涂覆的结构, 羊水干细胞存在下的抗菌活性和生物反应。 结果证明,所有沉积的样品都是纳米结构的,厚度低于1μm,显示出非常好的抗微生物效果,并且证明是适用于细胞粘附和增殖的合适的载体。

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