Poly-dimensional network comparative analysis reveals the pure pharmacological mechanism of baicalin in the targeted network of mouse cerebral ischemia

Liu Qiong; Liu Jun; Wang Pengqian; Zhang Yingying; Li Bing; Yu Yanan; Dang Haixia; Li Haixia; Zhang Xiaoxu; Wang Zhong

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Poly-dimensional network comparative analysis reveals the pure pharmacological mechanism of baicalin in the targeted network of mouse cerebral ischemia

机译：多维网络对比分析揭示了大鼠脑缺血靶向网络中黄芩苷的纯药理机制

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摘要

Aim: This study aimed to investigate the pure pharmacological mechanisms of baicalin/baicalein (BA) in the targeted network of mouse cerebral ischemia using a poly-dimensional network comparative analysis.

机译：目的：本研究旨在使用多维网络比较分析研究探讨脑病/巴卡斯坦（BA）在靶向网络中的纯药理学机制。

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来源
《Brain research》 |2017年第2017期|共10页
作者
Liu Qiong; Liu Jun; Wang Pengqian; Zhang Yingying; Li Bing; Yu Yanan; Dang Haixia; Li Haixia; Zhang Xiaoxu; Wang Zhong;
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作者单位

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

Beijing Univ Chinese Med Dongzhimen Hosp 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci Inst Informat Tradit Chinese Med 16 Nanxiaojie Beijing 100700;

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

China Acad Chinese Med Sci Inst Basic Res Clin Med 16 Nanxiaojie Beijing 100700 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
Poly-dimensional network comparative analysis; Pure pharmacological mechanism; Baicalin; Cerebral ischemia;

机译：多维网络比较分析;纯药理学机制;黄芩苷;脑缺血;

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专利

1. Poly-dimensional network comparative analysis reveals the pure pharmacological mechanism of baicalin in the targeted network of mouse cerebral ischemia [J] . Liu Qiong, Liu Jun, Wang Pengqian, Brain research . 2017,第期

机译：多维网络对比分析揭示了大鼠脑缺血靶向网络中黄芩苷的纯药理机制
2. Network pharmacology identification of mechanisms of cerebral ischemia injury amelioration by Baicalin and Geniposide [J] . Wu Jie, Wang Bin, Li Min, European Journal of Pharmacology: An International Journal . 2019,第期

机译：黄芩苷和栀子患者脑缺血损伤改善机制的网络药理学
3. Variation of pathways and network profiles reveals the differential pharmacological mechanisms of each effective component to treat middle cerebral artery ischemia-reperfusion mice [J] . Dang HaiXia, Li KangNing, Yu Yanan, Experimental Biology and Medicine: Journal of the Society for Experimental Biology and Medicine . 2016,第1期

机译：途径和网络概况的变化揭示了每种有效成分治疗大脑中动脉缺血再灌注小鼠的不同药理机制
4. High-density DNA microarray analysis of gene expression following transient focal cerebral ischemia in mouse [C] . Sheng T. Hou, Kevin G. Becker, Anne Baggley, International Symposium on Molecular Mechanism and Epochal Therapeutics for Ischemic Stroke and Dementia . 2003

机译：小鼠瞬时焦脑缺血后基因表达的高密度DNA微阵列分析
5. Integration of Alzheimer's Disease Genetics, Myeloid Cell Genomics and Gene Regulatory Networks Reveals Novel Disease Mechanisms, Drug Targets and Candidate Therapeutics [D] . Novikova, Gloriia. 2021

机译：阿尔茨海默病遗传学，骨髓细胞基因组学和基因监管网络的整合揭示了新型疾病机制，药物目标和候选治疗方法
6. Phenotype-dependent alteration of pathways and networks reveals a pure synergistic mechanism for compounds treating mouse cerebral ischemia [O] . Peng-qian Wang, Bing Li, Jun Liu, 2015

机译：依赖表型的途径和网络改变揭示了化合物治疗小鼠脑缺血的纯协同机制
7. Network Pharmacology Reveals the Mechanism of Activity of Tongqiao Huoxue Decoction Extract Against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia-Reperfusion Injury [O] . Si-peng Wu, Ning Wang, Li Zhao 2021

机译：网络药理学揭示了通桥Huoxue煎剂提取物对中脑动脉闭塞诱导的脑缺血再灌注损伤的活性机制

Poly-dimensional network comparative analysis reveals the pure pharmacological mechanism of baicalin in the targeted network of mouse cerebral ischemia

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