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Racial and ethnic disparities in hematologic malignancies

机译:血液学恶性肿瘤的种族和民族差异

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摘要

Racial and ethnic disparities in patients with solid malignancies have been well documented. Less is known about these disparities in patients with hematologic malignancies. With the advent of novel chemotherapeutics and targeted molecular, cellular, and immunologic therapies, it is important to identify differences in care that may lead to disparate outcomes. This review provides a critical appraisal of the empirical research on racial and ethnic disparities in incidence, survival, and outcomes in patients with hematologic malignancies. The review focuses on patients with acute myeloid leukemia, acute lymphocytic leukemia, multiple myeloma, non-Hodgkin lymphoma, Hodgkin lymphoma, myeloproliferative neoplasms, and myelodysplastic syndrome. The review discusses possible causes of racial and ethnic disparities and also considers future directions for studies to help decrease disparities.
机译:患有固体恶性肿瘤患者的种族和族裔差异已经充分记录。 较少是关于血液学恶性肿瘤患者的这些差异。 随着新型化学治疗剂和靶向分子,细胞和免疫疗法的出现,重要的是识别可能导致不同结果的护理差异。 本综述对血液学恶性肿瘤患者的发病率,生存和结果中的种族和种族差异和种族差异的实证研究提供了一项重要评价。 该综述重点介绍急性髓性白血病,急性淋巴细胞白血病,多发性骨髓瘤,非霍奇金淋巴瘤,霍奇金淋巴瘤,骨髓性肿瘤和骨髓增生综合征。 审查讨论了种族和民族差异可能的原因,并考虑了未来的研究指示,以帮助减少差异。

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