JAK2 V617F Dimerizes Homodimeric Cytokine Receptors Cytosolic Domains By Requiring Pseudokinase Domain Residues That Promote JAK2 Dimerization and Oncogenic Activity

Leroy Emilie; Balligand Thomas; Constantinescu Stefan N.

首页> 外文期刊>Blood: The Journal of the American Society of Hematology >JAK2 V617F Dimerizes Homodimeric Cytokine Receptors Cytosolic Domains By Requiring Pseudokinase Domain Residues That Promote JAK2 Dimerization and Oncogenic Activity

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JAK2 V617F Dimerizes Homodimeric Cytokine Receptors Cytosolic Domains By Requiring Pseudokinase Domain Residues That Promote JAK2 Dimerization and Oncogenic Activity

机译：JAK2 V617F通过需要促进JAK2二聚化和致癌活性的伪转基因酶结构域残基来二聚体细胞因子受体细胞溶质结构域

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来源
《Blood: The Journal of the American Society of Hematology》 |2018年第novaelatreatmentappr期|共2页
作者
Leroy Emilie; Balligand Thomas; Constantinescu Stefan N.;
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作者单位

Ludwig Inst Canc Res Brussels Branch Brussels Belgium;

Ludwig Inst Canc Res Brussels Branch Brussels Belgium;

Ludwig Inst Canc Res Brussels Branch Brussels Belgium;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
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1. JAK2 V617F Dimerizes Homodimeric Cytokine Receptors Cytosolic Domains By Requiring Pseudokinase Domain Residues That Promote JAK2 Dimerization and Oncogenic Activity [J] . Leroy Emilie, Balligand Thomas, Constantinescu Stefan N. Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：JAK2 V617F通过需要促进JAK2二聚化和致癌活性的伪转基因酶结构域残基来二聚体细胞因子受体细胞溶质结构域
2. Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation [J] . Ryan D Ferrao, Heidi JA Wallweber, Patrick J Lupardus eLife journal . 2018,第13期

机译：JAK2激活需要JAK2 FERM域的受体介导的二聚化
3. Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation [J] . Ryan D Ferrao, Heidi JA Wallweber, Patrick J Lupardus eLife journal . 2018,第july期

机译：JAK2激活需要JAK2 FERM域的受体介导的二聚化
4. Mixed-lineage kinase domain-like (MLKL) is a novel pseudokinase regulator of haematopoietic stem cell function, which modulates JAK2 signalling [C] . Murphy J.M., Tannahill G.M., Majewski I.J. Incorporating of the Australian Society for Biochemistry and Molecular Biology Combio . 2009

机译：混合谱系激酶域样（MLK1）是一种新型纯化干细胞功能的伪转酶调节剂，其调节JAK2信号传导
5. Targeting the Mutant JAK2 V617F Tyrosine Kinase by Small Molecules that Bind to its Pseudokinase Domain [D] . Puleo, David Edward 2018

机译：绑定到其假激酶结构域的小分子靶向突变的JAK2 V617F酪氨酸激酶。
6. Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation [O] . Ryan D Ferrao, Heidi JA Wallweber, Patrick J Lupardus 2015

机译：JAK2激活需要受体介导的JAK2 FERM域的二聚化
7. Faculty Opinions recommendation of Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation. [O] . Mitchell Weiss 2020

机译：jak2激活需要教师介导的jak2 ferm域的受体介导的二聚化的推荐。

JAK2 V617F Dimerizes Homodimeric Cytokine Receptors Cytosolic Domains By Requiring Pseudokinase Domain Residues That Promote JAK2 Dimerization and Oncogenic Activity

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