First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors

De Witte Moniek; Van Rhenen Anna; Van Sluis Geerte; Admiraal Rick; van der Wagen Lotte; Petersen Eefke J.; Raymakers Reinier; Minnema Monique C.; Janssen Anke; Westinga Kasper; Halkes Constantijn J. M.; Falkenburg J. H. Frederik; Boelens Jaap Jan; Kuball Jurgen

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First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors

机译：使用来自匹配相关和无关供体的成年患者的前瞻性I / II临床试验的前瞻性I / II临床试验结果

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来源
《Blood: The Journal of the American Society of Hematology》 |2018年第novaelatreatmentappr期|共3页
作者
De Witte Moniek; Van Rhenen Anna; Van Sluis Geerte; Admiraal Rick; van der Wagen Lotte; Petersen Eefke J.; Raymakers Reinier; Minnema Monique C.; Janssen Anke; Westinga Kasper; Halkes Constantijn J. M.; Falkenburg J. H. Frederik; Boelens Jaap Jan; Kuball Jurgen;
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作者单位

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

Univ Med Ctr Utrecht Pediat Utrecht Netherlands;

Univ Med Ctr Utrecht Lab Translat Immunol Utrecht Netherlands;

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

Univ Med Ctr Utrecht Lab Translat Immunol Utrecht Netherlands;

Univ Med Ctr Utrecht Cell Therapy Facil Utrecht Netherlands;

Leiden Univ Med Ctr Dept Hematol Leiden Netherlands;

Leiden Univ Med Ctr Dept Hematol Leiden Netherlands;

Univ Med Ctr Utrecht Utrecht Netherlands;

Univ Med Ctr Utrecht Hematol Utrecht Netherlands;

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原文格式 PDF
正文语种 eng
中图分类血液及淋巴系疾病;
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专利

1. First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors [J] . De Witte Moniek, Van Rhenen Anna, Van Sluis Geerte, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：使用来自匹配相关和无关供体的成年患者的前瞻性I / II临床试验的前瞻性I / II临床试验结果
2. TCR-Alpha/ Beta and CD19 Depleted Haploidentical Stem Cell Transplantation Following Reduced Intensity Conditioning in Children: First Results of a Prospective Multicenter Phase I/ II Clinical Trial [J] . Lang Peter J., Schlegel Paul G., Meisel Roland, Blood: The Journal of the American Society of Hematology . 2016,第22期

机译：儿童降低强度后，TCR-Alpha / Beta和CD19耗尽了单倍体干细胞移植：一项预期的多中心I / II期临床试验的初步结果
3. Alpha/Beta T-cell Depleted Allogenic Stem Cell Transplantation from Matched Related and Unrelated Donor Grafts in Patients with Poor Risk Leukemia [J] . de Witte Moniek, van der Wagen Lotte, Slaper-Cortenbach Ineke, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2015,第2Suppla1期

机译：配对的相关和不相关的供体移植物对风险较差的白血病患者的Alpha / Beta T细胞耗竭同种异体干细胞移植
4. DONOR-SPECIFIC (DSA) ANTI-DP ANTIBODIES ASSOCIATE WITH GRAFT FAILURE IN MATCHED UNRELATED DONOR HEMATOPOIETIC STEM CELL TRANSPLANTATION [C] . Stefan O. Ciurea, Fleur Aung, Pedro Cano, Clinical Histocompatibility Workshop. . 2010

机译：特异性（DSA）抗DP抗体与匹配的无关供体造血干细胞移植中的接枝衰竭相关联
5. Genetic Associations in Acute Leukemia Patients After Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation [D] . Rizvi, Abbas A. 2019

机译：匹配的无关供体同种异体造血干细胞移植后急性白血病患者的遗传协会。
6. Alpha/Beta T-Cell Depleted Grafts as an Immunological Booster to Treat Graft Failure after Hematopoietic Stem Cell Transplantation with HLA-Matched Related and Unrelated Donors [O] . E. Rådestad, H. Wikell, M. Engström, 2014

机译：Alpha / Beta T细胞衰竭移植物作为免疫增强剂可治疗与HLA匹配的相关和不相关供体的造血干细胞移植后的移植物衰竭
7. Alpha/Beta T-cell Depleted Allogeneic Stem Cell Transplantation from Matched Related and Unrelated Donor Grafts in Patients with Poor Risk Leukemia [O] . Witte Moniek de, der Wagen Lotte van, Slaper-Cortenbach Ineke, 2015

机译：配对的相关和不相关的供体移植物对风险较差的白血病患者的Alpha / Beta T细胞耗竭同种异体干细胞移植
8. Transplantation of Hematopoietic and Lymphoid Cells in Mice. H-2 Matched Unrelated Adult Donors Compared with H-2 Mismatched Fetal Donors. [R] . Bortin, M. M., Rimm, A. A., Rose, W. C., 1975

机译：造血和淋巴细胞移植在小鼠体内。 H-2匹配的无关成人捐赠者与H-2不匹配的胎儿捐赠者相比。

First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors

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