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Cardiometabolic Diseases and Related Complications: Current Status and Future Perspective

机译:心细素疾病和相关并发症:当前状态和未来的观点

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In the past decade, there has been a dramatic increase in chronic diseases like diabetes, hypertension, and obesity not only in industrialized nations but also in developing nations with emerging economies [1, 2]. With the escalation of obesity, diabetes and hypertension, there has been a parallel increase in the incidence and prevalence of cardiometabolic complications [3, 4]. Cardiometabolic complications are multifactorial diseases, and a wide spectrum of different factors including changes in living environments, diets, lifestyles, genetic, and epigenetic factors [1, 2] may be involved. Although significant strides have been made in elucidating the multifaceted mechanisms associated with many cardiometabolic complications [1, 2], much still has to be done. For example studies which unveil novel mechanisms implicated in cardiometabolic diseases may open new therapeutic horizons.
机译:在过去的十年中,糖尿病,高血压和肥胖等慢性疾病的急剧增加,不仅在工业化国家,而且在具有新兴经济体的发展中国家[1,2]。 随着肥胖症,糖尿病和高血压的升级,心脏异构并发症的发生率和患病率并平行增加[3,4]。 心细素并发症是多因素疾病,并且可以参与包括生物环境,饮食,生活方式,遗传和表观遗传因素[1,2]的变化的广泛的不同因素。 虽然已经进行了显着的趋势,但阐明了与许多心细镜型并发症相关的多方面机制[1,2],仍然必须进行。 例如,揭示涉及心细素疾病的新机制的研究可能开辟新的治疗视野。

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