On-line monitoring of Aspergillus niger GH1 growth in a bioprocess for the production of ellagic acid and ellagitannase by solid-state fermentation

摘要

Graphical abstractDisplay OmittedHighlights?CO2evolution was monitored in a bioprocess to produce ellagitannase and ellagic acid in SSF.?The use of maltose enhances the productivity of the process.?Two unknown compounds (M.W. 702 and 290g/mol) were identified and characterized by HPLC-MS/MS analysis.AbstractThe present work describes the monitoring of CO2production byAspergillus nigerGH1 in a bioprocess for the production of ellagitannase (EAH) and ellagic acid by solid state fermentation. Pomegranate ellagitannins, mainly punicalagin, were used as carbon source and EAH inducer. A second condition, using ellagitannins and maltose