Another One (of the “Undruggable” Targets) Bites the Dust: Discovery of a Potent and Selective Inhibitor of the Histone Acetyl Transferase p300/CBP

Thomas Kodadek

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Another One (of the “Undruggable” Targets) Bites the Dust: Discovery of a Potent and Selective Inhibitor of the Histone Acetyl Transferase p300/CBP

机译：另一个（“不可申请的”目标）咬尘埃：发现组蛋白乙酰转移酶P300 / CBP的有效和选择性抑制剂

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来源
《Biochemistry 》 |2018年第6期| 共2页
作者
Thomas Kodadek;
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Department of Chemistry The Scripps Research Institute 130 Scripps Way Jupiter Florida 33458 United States;

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正文语种 eng
中图分类生物化学 ;
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1. Another One (of the “Undruggable” Targets) Bites the Dust: Discovery of a Potent and Selective Inhibitor of the Histone Acetyl Transferase p300/CBP [J] . Thomas Kodadek Biochemistry . 2018 ,第6期

机译：另一个（“不可申请的”目标）咬尘埃：发现组蛋白乙酰转移酶P300 / CBP的有效和选择性抑制剂
2. Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor [J] . Wilson Jonathan E., Patel Gaurav, Patel Chirag, ACS medicinal chemistry letters . 2020 ,第6期

机译：CPI-1612的发现：有效，选择性和口服生物可利用的EP300 / CBP组氨酸乙酰转移酶抑制剂
3. Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases [J] . Michaelides Michael R., Kluge Arthur, Patane Michael, ACS medicinal chemistry letters . 2018 ,第1期

机译：发现螺氧唑氮二酮作为P300 / CBP组氨酸乙酰转移酶的选择性，口服生物可爱抑制剂
4. New Approach to Anacardic Acid related Histone Acetyl Transferase (HATs) Modulators(Abstracts) [C] . Jose A. Souto Salgado, Rosana Alvarez, Angel R. De Lera European Symposium on Organic Chemistry . 2007

机译：新嗜酸性酸相关组氨酸乙酰转移酶（帽）调节剂的新方法（摘要）
5. Histone acetyltransferase p300/CBP as a functionally significant target in melanoma. [D] . Yan, Gai. 2012

机译：组蛋白乙酰转移酶p300 / CBP是黑色素瘤中功能上重要的靶标。
6. Discovery of CPI-1612: A Potent Selective and Orally Bioavailable EP300/CBP Histone AcetyltransferaseInhibitor [O] . Jonathan E. Wilson, *, Gaurav Patel, 2020

机译：CPI-1612的发现：一种有效的选择性和口服生物可利用的EP300 / CBP组氨酸乙酰转移酶抑制剂
7. Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor [O] . -1

机译：CPI-1612的发现：一种有效的，选择性和口服生物可利用的EP300 / CBP组氨酸乙酰转移酶抑制剂

Another One (of the “Undruggable” Targets) Bites the Dust: Discovery of a Potent and Selective Inhibitor of the Histone Acetyl Transferase p300/CBP

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