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Reconstruction of fMRI Signal Using Near-Infrared Optical Imaging Technique

机译:近红外光学成像技术重建FMRI信号

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It is well known that both functional magnetic resonance imaging (fMRI) and near-infrared optical imaging (NIRO Imaging) techniques reflect the hemodynamic change associated with alteration in local brain activity. The former reflects a difference in the magnetic susceptibility between blood vessels and surrounding tissue caused by changes in paramagnetic deoxygenated hemoglobin (deoxy-Hb) concentration in the flowing blood, whereas the latter more directly reflects changes in concentrations of both deoxy-Hb and diamagnetic oxygenated hemoglobin (oxy-Hb). In the present study, we aim to clarify the physiological interpretations of data obtained with fMRI and NIRO Imaging during sensory stimulation in humans. Further, we show a successful description of the fMRI signal as a function of concentrations of deoxy-Hb and oxy-Hb obtained with NIRO Imaging.
机译:众所周知,既有功能磁共振成像(FMRI)和近红外光学成像(NIRO成像)技术都反映了与局部脑活动改变相关的血流动力学变化。 前者反映了通过流动血液中的顺磁性脱氧血红蛋白(脱氧-Hb)浓度的变化引起的血管和周围组织之间的磁化率差异,而后者更直接反映脱氧-Hb和硅氧化浓度的变化 血红蛋白(Oxy-HB)。 在本研究中,我们的目的是阐明在人类的感觉刺激期间用FMRI和NIRO成像获得的数据的生理解释。 此外,我们表明FMRI信号的成功描述作为用Niro成像获得的脱氧-Hb和氧-Hb的浓度的函数。

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