The prevalence of drug-related acute pancreatitis in children ranges from 3 to 20%. Common medications implicated include asparaginase, antiepileptics, steroids and sulphur-based drugs Propofol is increasingly used to sedate patients for procedural sedation and mechanical ventilation. Infusion rates up to 30 mg/kg/hour have been used in children2'3. The postulated mechanism of propofol-induced pancreatitis is due to raised triglyceride level as propofol is a lipid-based drug.
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机译：儿童与药物相关的急性胰腺炎的患病率为3％至20％。涉及的常见药物包括天冬酰胺酶，抗癫痫药，类固醇和以硫为基础的药物丙泊酚越来越多地用于使患者镇静以进行程序镇静和机械通气。儿童2'3的输注速度高达30 mg / kg /小时。丙泊酚诱发的胰腺炎的推测机制是由于丙泊酚是一种基于脂质的药物，因此甘油三酯水平升高。
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