Polycyclic Guanidine Natural Products: Total Synthesis of Batzelladines

摘要

In nature, there are a number of natural products containing guanidine moiety. Among them, polycyclic guanidine compounds have attracted considerable attention from synthetic chemists and biologists because of their architecturally intriguing structures and potent biological activities. This short review summarizes synthetic methodologies toward batzelladines focusing on stereoselective construction of the core tricyclic guanidine skeleton.