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Residential distance to high-voltage power lines and risk of neurodegenerative diseases: A danish population-based case-control study

机译:距高压电线的住宅距离和神经退行性疾病的风险:基于丹麦人群的病例对照研究

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摘要

The aim of this study was to investigate the possible association between residential distance to high-voltage power lines and neurodegenerative diseases, especially Alzheimer's disease. A Swiss study previously found increased risk of Alzheimer's disease for people living within 50 m of a power line. A register-based case-control study including all patients diagnosed with neurodegenerative diseases during the years 1994-2010 was conducted among the entire adult population of Denmark. Using conditional logistic regression models, hazard ratios for ever living close to a power line in the time period 5-20 years before diagnosis were computed. The risks for developing dementia, Parkinson's disease, multiple sclerosis, and motor neuron disease were not increased in persons living within close vicinity of a power line. The risk of Alzheimer's disease was not increased for ever living within 50 m of a power line (hazard ratio = 1.04, 95% confidence interval: 0.69, 1.56). No dose-response according to number of years of living within 50 m of a power line was observed, but there were weak indications of an increased risk for persons diagnosed by the age of 75 years. Overall, there was little support for an association between neurodegenerative disease and living close to power lines.
机译:这项研究的目的是调查居住在距高压电源线的距离与神经退行性疾病,尤其是阿尔茨海默氏病之间的可能联系。之前的一项瑞士研究发现,居住在电力线50 m以内的人们患阿尔茨海默氏病的风险增加。在丹麦的整个成年人群中,进行了基于登记的病例对照研究,其中包括1994-2010年期间所有被诊断患有神经退行性疾病的患者。使用条件逻辑回归模型,计算出诊断前5-20年内居住在电力线附近的危险比。生活在电源线附近的人患痴呆症,帕金森氏病,多发性硬化症和运动神经元疾病的风险没有增加。生活在距离电力线50 m以内的地区,患阿尔茨海默氏病的风险并未增加(危险比= 1.04,95%置信区间:0.69,1.56)。没有观察到根据生活在电力线50 m以内的年数的剂量反应,但是没有迹象表明75岁以下的人被诊断出的风险增加。总体而言,几乎没有人支持神经退行性疾病与生活在电力线附近的联系。

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