Angiotensin Blockade and Progressive Loss of Kidney Function in Hemodialysis Patients: A Randomized Controlled Trial

Kjaergaard Krista Dybtved; Peters Christian Daugaard; Jespersen Bente; Tietze Ida Norager; Madsen Jens Kristian; Pedersen Birgitte Bang; Novosel Marija Kristina; Laursen Kathrine Skaaning; Bibby Bo Martin; Strandhave Charlotte; Jensen Jens Dam

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Angiotensin Blockade and Progressive Loss of Kidney Function in Hemodialysis Patients: A Randomized Controlled Trial

机译：血液透析患者的血管紧张素阻滞和肾脏功能进行性丧失：一项随机对照试验

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Background: Glomerular filtration rate (GFR) declines during long-term dialysis treatment. In peritoneal dialysis, blockade of the renin-angiotensin-aldosterone system reduces GFR decline. Observational studies suggest that similar treatment may preserve kidney function in hemodialysis (HD).

机译：背景：长期透析治疗期间肾小球滤过率（GFR）下降。在腹膜透析中，肾素-血管紧张素-醛固酮系统的阻滞减少了GFR的下降。观察性研究表明，类似的治疗可以在血液透析（HD）中保留肾脏功能。

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《American Journal of Kidney Diseases: The official journal of the National Kidney Foundation》 |2014年第6期|共10页
作者
Kjaergaard Krista Dybtved; Peters Christian Daugaard; Jespersen Bente; Tietze Ida Norager; Madsen Jens Kristian; Pedersen Birgitte Bang; Novosel Marija Kristina; Laursen Kathrine Skaaning; Bibby Bo Martin; Strandhave Charlotte; Jensen Jens Dam;
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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
Adult; albuminuria; aldosterone; angiotensin II; angiotensin II receptor blocker; anuria; double-blinded; glomerular filtration rate (GFR); GFR decline; hemodialysis (HD); investigator-initiated; irbesartan; multicenter study; placebo; preservation of residual renal function; randomized controlled trial; renin; residual renal function; SAFIR (Saving Residual Renal Function in Hemodialysis Patients Receiving Irbesartan) trial; urine volume;

机译：成人;白蛋白尿;醛固酮;血管紧张素II;血管紧张素II受体阻滞剂;无尿;双盲;肾小球滤过率（GFR）;GFR下降;血液透析（HD）;研究者发起;厄贝沙坦;多中心研究;安慰剂;残余肾保存功能;随机对照试验;肾素;残余肾功能;SAFIR（保存接受厄贝沙坦的血液透析患者的残余肾功能）试验;尿量;

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1. Angiotensin Blockade and Progressive Loss of Kidney Function in Hemodialysis Patients: A Randomized Controlled Trial [J] . Kjaergaard Krista Dybtved, Peters Christian Daugaard, Jespersen Bente, American Journal of Kidney Diseases: The official journal of the National Kidney Foundation . 2014,第6期

机译：血液透析患者的血管紧张素阻滞和肾脏功能进行性丧失：一项随机对照试验
2. Effect of continuous progressive resistance training during hemodialysis on body composition, physical function and quality of life in end-stage renal disease patients: a randomized controlled trial [J] . da Costa Rosa Clara Suemi, Nishimoto Danilo Yuzo, Damasceno e Souza Giovana, Clinical rehabilitation . 2018,第7期

机译：血液透析在血液透析期间的慢性渐进性抗性训练对末期肾病患者身体成分，物理功能和生活质量的影响：随机对照试验
3. Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials [J] . Hiremath Swapnil, Fergusson Dean A., Fergusson Nicholas, American Journal of Kidney Diseases: The official journal of the National Kidney Foundation . 2017,第1期

机译：肾移植受者的肾素 - 血管紧张素系统封锁和长期临床结果：随机对照试验的荟萃分析
4. Combined Brainwave Synchronizer with Progressive Muscle Relaxation on the Maintained Hemodialysis Patients: A Randomly Controlled Study [C] . Yongmei Hou, Peicheng Hu, Mei Wang, SREE Workshop on Medical Materials and Engineering . 2012

机译：组合脑波同步器与维持血液透析患者的渐进式肌肉放松：随机对照研究
5. The effect of maintaining high hemoglobin levels on long-term kidney function in kidney transplant recipients: a randomized controlled trial [D] . Tsujita Makoto, 辻田誠 2019

机译：维持高血红蛋白水平对肾移植受者长期肾脏功能的影响：一项随机对照试验
6. High-sensitivity Troponin T in hemodialysis patients: a randomized placebo-controlled sub-study investigating angiotensin-II-blockade variation over time and associations with clinical outcome [O] . Christian D. Peters, Krista D. Kjaergaard, Kent L. Christensen, 2020

机译：血液透析患者的高敏感性肌钙蛋白T：一种随机安慰剂控制的血管紧张素 - II阻断随时间变化和临床结果的关联
7. Antihypertensive and cardiovascular effects of combined blockade of renin-angiotensin system with ACE inhibitor and angiotensin II type 1 receptor blocker in hypertensive patients: A 24-week randomized controlled double-dummy trial [O] . Giuseppe Licata, Salvatore Corrao, Gaspare Parrinello, 2010

机译：高血压患者联合阻断肾素 - 血管紧张素系统与aCE抑制剂和血管紧张素II 1型受体阻滞剂的抗高血压和心血管作用：一项为期24周的随机对照双模拟试验

Angiotensin Blockade and Progressive Loss of Kidney Function in Hemodialysis Patients: A Randomized Controlled Trial

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