首页> 外文期刊>American Journal of Kidney Diseases: The official journal of the National Kidney Foundation >PHARMACOLOGICAL PROFILE OF KBP-5074, A NOVEL NON STEROIDAL, HIGHLY SELECTIVE, MINERALOCORTICOID RECEPTOR ANTAGONIST (NIRA) FOR THE TREATMENT OF CARDIORENAL DISEASES

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PHARMACOLOGICAL PROFILE OF KBP-5074, A NOVEL NON STEROIDAL, HIGHLY SELECTIVE, MINERALOCORTICOID RECEPTOR ANTAGONIST (NIRA) FOR THE TREATMENT OF CARDIORENAL DISEASES

机译：KBP-5074的药理学档案，一种新型非甾体类，高度选择性的类糖皮质激素受体拮抗剂（NIRA），用于治疗心血管疾病。

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《American Journal of Kidney Diseases: The official journal of the National Kidney Foundation》 |2016年第5期|共1页
作者
Zhang B.; Tan X. J.; Wang Y. L.;
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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. PHARMACOLOGICAL PROFILE OF KBP-5074, A NOVEL NON STEROIDAL, HIGHLY SELECTIVE, MINERALOCORTICOID RECEPTOR ANTAGONIST (NIRA) FOR THE TREATMENT OF CARDIORENAL DISEASES [J] . Zhang B., Tan X. J., Wang Y. L. American Journal of Kidney Diseases: The official journal of the National Kidney Foundation . 2016,第5期

机译：KBP-5074的药理学档案，一种新型非甾体类，高度选择性的类糖皮质激素受体拮抗剂（NIRA），用于治疗心血管疾病。
2. Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases [J] . Lars Barfacker, Alexander Kuhl, Alexander Hillisch ChemMedChem . 2012,第8期

机译：BAY 94-8862的发现：盐皮质激素受体的非甾体类拮抗剂，可用于治疗心血管疾病
3. Pharmacokinetics, distribution, and disposition of esaxerenone, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist, in rats and monkeys [J] . Yamada Makiko, Takei Makoto, Suzuki Eiko, Xenobiotica: the fate of foreign compounds in biological systems . 2017,第1a12期

机译：esaxerenone的药代动力学，分布和处置，一种新颖，高效和选择性非甾体矿物质皮质激素受体拮抗剂，大鼠和猴子
4. Design and synthesis of cyclic peptide antagonists intended to block coactivator binding to steroid nuclear receptors [C] . Anne-Marie Leduc, Kelli S.Bramlett, Thomas P.Burris, the International Peptide Symposium . 2001

机译：旨在阻断与类固醇核受体结合的循环肽拮抗剂的设计和合成
5. Steroid hormone withdrawal alters the GABA(A) receptor pharmacological profile: An electrophysiological study. [D] . Hsu, Fu-Chun (Robert). 2000

机译：类固醇激素撤药改变了GABA（A）受体的药理特性：一项电生理研究。
6. The Non-Steroidal Mineralocorticoid Receptor Antagonist KBP-5074 Limits Albuminuria and has Improved Therapeutic Index Compared With Eplerenone in a Rat Model With Mineralocorticoid-Induced Renal Injury [O] . Frédéric Jaisser, Xiaojuan Tan, Shuangshuang Chi, 2021

机译：非甾体矿物皮质激素受体拮抗剂KBP-5074限制白蛋白尿素并改善了与大鼠模型中的ePlerenone相比具有矿物质皮质激素诱导的肾损伤的ePlerenone
7. Cover Picture: Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases (ChemMedChem 8/2012) [O] . Lars Bärfacker, Alexander Kuhl, Alexander Hillisch, 2012

机译：封面图片：发现海湾94-8862：用于治疗生物皮质激素受体的非甾体拮抗剂（ChemMedchem 8/2012）

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