External validation of the BIS (Berlin Initiative Study)-1 GFR estimating equation in the elderly

摘要

Surgeons often use spinal fixators to manage spinal instability. Dynesys (DY) is a type of dynamic fixator that is designed to restore spinal stability and to provide flexibility. The aim of this study was to design a new spinal fixator using topology optimization [the topology design (TD) system]. Here, we constructed finite element (FE) models of degenerative disc disease, DY, and the TD system. A hybrid-controlled analysis was applied to each of the three FE models. The rod structure of the topology optimization was modelled at a 39 % reduced volume compared with the rigid rod. The TD system was similar to the DY system in terms of stiffness. In contrast, the TD system reduced the cranial adjacent disc stress and facet contact force at the adjacent level. The TD system also reduced pedicle screw stresses in flexion, extension, and lateral bending.