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Facile and Multiple Replication of Superhydrophilic-Superhydrophobic Patterns Using Adhesive Tape

机译:使用胶带轻松和多次复制超亲水-超疏水模式

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摘要

Surfaces patterned with both hydrophilic and hydrophobic regions are useful in a variety of applications. For example, they can be used as surface tension-confined microchannels, in paper-based microfluidics, or for patterning cells. To create a new patterned substrate, usually the entire experimental procedure must be repeated, which can be time-consuming and laborious. In this paper, we present a simple and fast method that allows the transfer of superhydrophilic—super hydrophobic micropatterns in porous polymer films onto adhesive tape. Replicating patterns using adhesive tape is economical, as the fabrication of one patterned substrate can be used to create multiple copies of the micropatterns, which can then be used for several different experiments. We demonstrate that at least twelve consecutive copies can be made from 12S μm-thick patterned polymer films. Since the polymer film is transferred to adhesive tape, which is flexible, the copies can be used on curved surfaces and they can also be cut into different shapes and sizes. We also demonstrate an application of the replicated patterned polymer surfaces as a substrate for reverse cell transfection experiments.
机译:具有亲水和疏水区域的图案的表面可用于多种应用中。例如,它们可以用作表面张力受限的微通道,用于基于纸张的微流体中,或用于对细胞进行图案化。为了产生新的图案化基板,通常必须重复整个实验过程,这可能是费时且费力的。在本文中,我们提出了一种简单而快速的方法,该方法可以将多孔聚合物薄膜中的超亲水超疏水微图案转移到胶带上。使用胶带复制图案是经济的,因为一个图案化基板的制造可用于创建微图案的多个副本,然后可将其用于几个不同的实验。我们证明至少可以由12Sμm厚的图案化聚合物薄膜制成十二个连续副本。由于将聚合物薄膜转移到柔软的胶带上,因此可以在曲面上使用副本,也可以将副本切成不同的形状和尺寸。我们还演示了复制的图案化聚合物表面作为反向细胞转染实验的底物的应用。

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