Genetics and the Future ot Clinical Psychiatry

摘要

The field of human genetics has advanced rapidly in the past 50 years, from the determination of the correct number of human chromosomes to the development of a reference map of the approximately 25,000 genes in the human genome. Moreover, we are now systematically identifying common variations in the DNA sequence of the human family (1) that likely affect the biological processes that contribute to individual differences in behavior. Although uncertainties abound (e.g., the definition of a gene is still under revision ), the integration of human genetics and neuroscience is leading to major advances in our understanding of the biology of human mental health and disease.