Hard outcomes: clinical trials to reduce suicide.

摘要

Suicide accounts for nearly 12 in 100,000 deaths in the United States each year, making it the third leading cause of death among individuals ages 15-24 and fourth among those ages 25-44 (1). Individuals with mood disorders are around 20 times more likely than the general population to die by suicide-and this is likely an underestimate, as it misses misclassified accidents and deaths among people who do not live long enough to have their illness diagnosed (2).