Near-Infrared (NIR) Spectral Signature Development and Validation for Counterfeit Drug Detection Using Portable Spectrometer

摘要

Pharmaceutical industry and federal agencies are finding ways globally to counteract the increasing threats caused by pharmaceutical counterfeiting [1]. Recent estimates are that perhaps 15% of pharmaceutical drugs world-wide are counterfeited [2]. Several technologies are currently available to detect counterfeit drugs rapidly and efficiently. These include covert and overt features added to the packaging material and to the drug product itself, and authenticating the suspect drug for these features [3]. Another effective technique is to develop unique spectral signatures for the drug product and to test the suspect product against these signatures in order to spot counterfeits and also to authenticate legitimate products.