Drug Delivery

摘要

Catalent has invested in developing technologies focused on enhancing solubility and bioavailability of drugs, as these are key challenges to successful drug delivery. There are many approaches in this field, including chemical modification, particle size reduction, and hot melt extrusion to produce stable, amorphous dispersions, and lipid-based formulations. With over 80 years of softgel formulation experience with RP Scherer softgel technology, recent innovations include OptiShell? Technology, a soft, gelatin-free encapsulation which allows for higher melting point fill formulations, and is also capable of modifying the release of poorly soluble and/or poorly permeable drug compounds.