Optimization of cell growth and poly (glutamic acid) production in batch fermentation by Bacillus subtilis

Andrew Richard; Argyrios Margaritis

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Optimization of cell growth and poly (glutamic acid) production in batch fermentation by Bacillus subtilis

机译：枯草芽孢杆菌分批发酵中细胞生长和聚谷氨酸生产的优化

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Poly (glutamic acid) was produced maximally by Bacillus subtilis in batch fermentations at pH 7 and using glycerol at 20 g l~(-1) in a glutamic acid/citric acid medium. Poly (glutamic acid) reached 23 g l~(-1) after 30 h.

机译：枯草芽孢杆菌在pH 7的分批发酵中，并在谷氨酸/柠檬酸培养基中使用20 g l〜（-1）的甘油，可最大程度地产生聚谷氨酸。 30 h后聚谷氨酸达到23 g l〜（-1）。

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《Biotechnology Letters》 |2003年第6期|共4页
作者
Andrew Richard; Argyrios Margaritis;
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正文语种 eng
中图分类生物工程学（生物技术）;生命科学总论;分子生物学;
关键词
biopolymer pharmaceuticals; drug delivery; fermentation; paclitaxel; poly (glutamic acid);

机译：生物聚合物药物;药物输送;发酵;紫杉醇;聚谷氨酸;

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专利

1. Optimization of cell growth and poly (glutamic acid) production in batch fermentation by Bacillus subtilis [J] . Andrew Richard, Argyrios Margaritis Biotechnology Letters . 2003,第6期

机译：枯草芽孢杆菌分批发酵中细胞生长和聚谷氨酸生产的优化
2. The statistically optimized production of poly(gamma-glutamic acid) by batch fermentation of a newly isolated Bacillus subtilis RKY3 [J] . Jeong JH, Kim JN, Wee YJ, Bioresource Technology: Biomass, Bioenergy, Biowastes, Conversion Technologies, Biotransformations, Production Technologies . 2010,第12期

机译：通过新分离的枯草芽孢杆菌RKY3的分批发酵在统计学上优化生产聚（γ-谷氨酸）
3. Optimization of Bacillus subtilis cell growth effecting Jiean–peptide production in fed batch fermentation using central composite design [J] . Zhong Juan, Zhang Xiaoyong, Ren Yanli, Electronic Journal of Biotechnology . 2014,第3期

机译：使用中心复合设计优化补料分批发酵中影响芽孢杆菌肽生产的枯草芽孢杆菌细胞生长
4. Optimization of Bacillus subtilis FED-Batch Fermentations For the Maximization of the Synthesis of A Recombinant [C] . C.Shene, B.Andrews, J.A.Asenjo Computer applications in biotechnology 1998(CAB7) : Horizon of BioProcess systems engineering in 21st century . 1998

机译：枯草芽孢杆菌FED分批发酵的优化，可最大程度地合成重组子
5. Kinetics and modeling of cell growth and poly(glutamic acid) production by Bacillus subtilis [D] . Richard, Andrew 2005

机译：枯草芽孢杆菌细胞生长和聚谷氨酸生产的动力学和建模
6. Characterization of a Generalized Transducing Phage of Poly-(gamma)-Glutamic Acid-Producing Bacillus subtilis and Its Application for Analysis of Tn917-LTV1 Insertional Mutants Defective in Poly-(gamma)-Glutamic Acid Production [O] . T. Nagai, Y. Itoh 1997

机译：产生γ-聚谷氨酸的枯草芽孢杆菌广义转导噬菌体的表征及其在聚γ-谷氨酸生产中缺陷Tn917-LTV1插入突变体分析中的应用
7. Optimization of Bacillus subtilis cell growth effecting jiean-peptide production in fed batch fermentation using central composite design [O] . Zhong, Juan, Zhang, Xiaoyong, Ren, Yanli, 2014

机译：使用中央复合设计优化补料分批发酵中影响解节肽生产的枯草芽孢杆菌细胞生长
8. D isomer Composition of Bacillus anthracis Poly-Gamma-Glutamic Acid Capsule Reduces Host Immune Responses. [R] . Jelacic, T. M., Ribot, W. J., Chua, J., 2016

机译：炭疽芽孢杆菌聚-γ-谷氨酸胶囊的D异构体组成减少宿主免疫应答。

Optimization of cell growth and poly (glutamic acid) production in batch fermentation by Bacillus subtilis

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