Recent advances in marine drug research.

摘要

Structures and properties of promising marine anti-cancer, anti-inflammation and anti-infectious (HIV, HSV, malaria, leishmania) compounds reported during 2008-2011 are discussed. Wherever possible, attempts have also been made to highlight their possible biogenesis or structure-activity relationships (SAR). Since the stress is on identifying and short-listing potential drug molecules, this review is restricted to only those compounds exhibiting promising in vitro activity, the arbitrary cut off being IC₅₀ <15 micro M, reported during the above period.Digital Object Identifier http://dx.doi.org/10.1016/j.biotechadv.2013.02.006