1,6-anhydro-N-acetyl-#beta#-D-glucosamine in the oligosaccharide syntheses. I. Synthesis of 3-acetate and 3-benzoate of 1,6-anhydro-N-acetyl-#beta#-D-glucosamine via the 4-O-trityl derivative

摘要

3-O-Acethl and 3-O-benzoyl derivatives of 1,6-anhydro-N-acetyl-#beta#-D-glucosamine were synthesized via its selective tritylation followed by the 3-O-acylation and removal of the trityl protective group. Tritylium trifluoromethanesulfonate, which can easily be prepared by mixing solutions of triphenylcarbinol and trimethylsilyl trifluoromethanesulfonate in an equimolar ratio, was suggested as a reagent for the effective tritylation of a secondary hydroxyl group.