Monkey viral pathology in the Sukhum colony and modeling human viral infections

Lapin Boris A.; Shevtsova Zinaida V.

摘要

Abstract >The data characterizing spontaneous infections of Old World monkeys: measles, poliomyelitis, hepatitis A (HPA), encephalomyocarditis, coronavirus infection, simian hemorrhagic fever (SHF), are presented. The experimental infections were reproduced with the isolated pathogens. On these models, pathogenesis and epidemiology of these diseases were studied. The efficiency of poliomyelitis, measles and HPA vaccines is shown. The priority of data on the discovery of earlier unknown disease—SHF and “Sukhumi” virus—are emphasized. Several important pathogenic mechanisms common for various hemorrhagic fevers were studied on experimental SHF of macaques. This model is uniquely safe and adequate for the assessment of therapy of hemorrhagic fevers dangerous for humans. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“main”XML：ID =“JMP12351-ABS-AB-ABS-0001”XML：Lang =“EN”> <标题类型=“main”>抽象</ title> >数据表征旧世界自发性感染的数据猴子：麻疹，脊髓灰质炎，甲型肝炎，癌症，脑膜炎，冠状病毒感染，猿猴出血热（SHF）。用分离的病原体再现实验感染。在这些模型中，研究了这些疾病的发病机制和流行病学。显示了脊髓灰质炎，麻疹和HPA疫苗的效率。强调了关于早期未知疾病-SHF和“sukhumi”病毒的发现数据的优先权。研究了各种出血性杂交常见的几种重要致病机制，在Macaques的实验SHF上进行了研究。该模型是独特的安全性，适当地评估对人类危险的出血性射击的治疗。</ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-36449/'>《Journal of medical primatology》</a> <b style="margin: 0 2px;">|</b><span>2018年第4期</span><b style="margin: 0 2px;">|</b><span>共5页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lapin Boris A.&option=202" target="_blank" rel="nofollow">Lapin Boris A.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Shevtsova Zinaida V.&option=202" target="_blank" rel="nofollow">Shevtsova Zinaida V.;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Research Institute of Medical PrimatologySochi Russia;</p> <p>Research Institute of Experimental Pathology and Therapy of the Abkhazian Academy of SciencesSukhum Abkhazia;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/40383.html" title="灵长目">灵长目;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=encephalomyocarditis&option=203" rel="nofollow">encephalomyocarditis;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=hepatitis A&option=203" rel="nofollow">hepatitis A;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=measles&option=203" rel="nofollow">measles;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=poliomyelitis&option=203" rel="nofollow">poliomyelitis;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=simian hemorrhagic fever&option=203" rel="nofollow">simian hemorrhagic fever;</a> </p> <div class="translation"> 机译：脑膜炎;甲型肝炎;麻疹;脊髓灰质炎;猿猴性出血热; 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Tan,</a> <a href="/journal-foreign-20471/" target="_blank" rel="nofollow" class="tuijian_authcolor">Infection and immunity .</a> <span>1974</span><span>,第4期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：人类在病毒感染过程中的细胞介导的免疫：轻度病毒性呼吸道感染期间的皮肤超敏反应和体外淋巴细胞增殖</span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-273689_thesis/0705015544397.html">AN EPIDEMIOLOGICAL MODEL OF VIRAL INFECTIONS IN A VARR OA-INFESTED BEE COLONY: THE CASE OF A BEE-DEPENDENT MITE POPULATION SIZE</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=SARA BERNARDI&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">SARA BERNARDI,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=EZIO VENTURINO&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">EZIO VENTURINO </a> <a href="/conference-foreign-273689/" target="_blank" rel="nofollow" class="tuijian_authcolor">International Symposium on Mathematical and Computational Biology .</a> <span>2017</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：Vart OA侵染蜂殖民地病毒感染的流行病学模型：蜜蜂依赖性螨虫大小的情况</span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-degree-foreign_mphd_thesis/02061821135.html">Targeted deletion of Fgl2 enhances anti-viral T cell responses and mediates viral clearance in a murine model of chronic viral infection</a> <b>[D] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Luft, Olga&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Luft, Olga </a> <span>2014</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：针对FL1的靶向缺失增强了抗病毒T细胞应答并在慢性病毒感染的小鼠模型中介导病毒清除</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/04000210728.html">Note: Variability of Viral Load in Plasma of Rhesus Monkeys Inoculated with Simian Immunodeficiency Virus or Simian-Human Immunodeficiency Virus: Implications for Using Nonhuman Primate AIDS Models To Test Vaccines and Therapeutics</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Robert A. 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target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Shingai Yasuhiro,</a> <span>2008</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：恒河猴和食蟹猴TRIM5αs对人类免疫缺陷病毒2型感染的抗病毒活性比较</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_progress-veterinary-medicine_thesis/0201260770791.html">H5N1流感病毒感染恒河猴短期和恢复期病理学观察</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=闵凡贵&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 闵凡贵</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张钰&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张钰</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=赵维波&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,赵维波</a> <span> <a href="/journal-cn-7069/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 动物医学进展 </a> </span> <span> . 2006</span><span>,第006期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_detail_thesis/0201297320007.html">甲型肝炎病毒感染狨猴后的肝脏病理学观察</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=沈菊阳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 沈菊阳</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=马东林&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,马东林</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈天培&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,陈天培</a> <span> <a href="/journal-cn-56819/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 上海医学 </a> </span> <span> . 1990</span><span>,第2期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-clinical-experimental-medicine_thesis/0201240852888.html">人类免疫缺陷病毒感染相关淋巴瘤的临床病理学观察</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张淑红&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 张淑红</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=柳玮华&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,柳玮华</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=杨艳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,杨艳</a> <span> <a href="/journal-cn-12940/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 临床和实验医学杂志 </a> </span> <span> . 2014</span><span>,第005期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" 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href="/academic-journal-cn_chinese-journal-experimental-clinical-infectious-diseases-electronic-edition_thesis/0201291767543.html">8369例人类免疫缺陷病毒感染/获得性免疫缺陷综合征患者合并乙型肝炎病毒和(或)丙型肝炎病毒感染临床分析</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=覃亚勤&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 覃亚勤</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=秦英梅&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,秦英梅</a> <span> <a href="/journal-cn-6128/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中华实验和临床感染病杂志（电子版） </a> </span> <span> . 2021</span><span>,第005期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-28669_thesis/020222053093.html">SARS冠状病毒感染恒河猴的病毒、血清学检测</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=魏强&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 魏强</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王健伟&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,王健伟</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张扬清&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张扬清</a> <span> <a href="/conference-cn-28669/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国实验动物学会第六届学术年会 </a> <span> <span> . 2004</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/02031877212.html">SARS冠状病毒感染恒河猴和食蟹猴的病理学及其相关研究</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=邓巍&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 邓巍</a> <span> . 2005</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06120101631856.html">在接受抗逆转录病毒治疗的对象中诱导针对人类免疫缺陷病毒感染的免疫应答的方法</a> <b>[P]</b> . <span> 中国专利： CN110494159A </span> <span> . 2019-11-22</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120104505532.html">用于治疗人类获得性免疫缺陷病毒和其它病毒感染的组合物</a> <b>[P]</b> . <span> 中国专利： CN1301158A </span> <span> . 2001-06-27</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130437145000.html">Use of a pharmaceutical composition for the treatment of pathologies derived from infection by herpes virus, papillomavirus, hepatitis virus, viral neuralgia, viral dsyplasia, immune-deficiency-induced viral infections and viral neuritis.</a> <b>[P]</b> . <span> 外国专利：  EP1627663A2 </span> <span> . 2006-02-22</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：药物组合物在治疗由疱疹病毒，乳头瘤病毒，肝炎病毒，病毒性神经痛，病毒异型增生，免疫缺陷引起的病毒感染和病毒性神经炎引起的病理学中的用途。 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130437144999.html">Use of a pharmaceutical composition for the treatment of pathologies derived from infection by herpes virus, papillomavirus, hepatitis virus, viral neuralgia, viral dsyplasia, immune-deficiency-induced viral infections and viral neuritis.</a> <b>[P]</b> . <span> 外国专利：  EP1627663A3 </span> <span> . 2006-03-15</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：药物组合物在治疗由疱疹病毒，乳头瘤病毒，肝炎病毒，病毒性神经痛，病毒异型增生，免疫缺陷引起的病毒感染和病毒性神经炎引起的病理学中的用途。 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130460442539.html">USE OF A COMPOUND, SUBSTANCE OR COMPOSITION, IN THE PREPARATION OF A SUBSTANCE OR COMPOSITION TO TREAT A VIRAL INFECTION, COMPOUND, SUBSTANCE OR COMPOSITION, THEIR USES FOR, TREATMENT OF A VIRAL INFECTION, AS A TREATMENT OR MEDICATION FROM A VIRAL INFECTION; MEDICINE OR MEDICINE, PROCESS OF PREPARING A COMPOUND AND PROCESS OF TREATING A VIRAL INFECTION IN A HUMAN OR ANIMAL BEING</a> <b>[P]</b> . <span> 外国专利：  BR9303733A </span> <span> . 1994-03-15</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：在制备用于治疗病毒感染，化合物，物质或成分的物质或组合物中使用化合物，物质或组合物，将其用于治疗病毒感染，作为病毒感染的治疗或药物的用途;药物，制备化合物的过程以及治疗人类或动物的病毒感染的过程 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" 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