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Simian immunodeficiency virus infection and flow cytometric characterization of Japanese macaque ( Macaca fuscataMacaca fuscata ) hematopoietic cells

机译:猿猴免疫缺陷病毒感染和日本猕猴的流式细胞术表征( 麦卡拉fuscata 麦卡法 )造血细胞

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Abstract > We characterized Japanese macaque ( Macaca fuscata ) hematopoietic cells using flow cytometry and identified 28 cross‐reactive anti‐human antibody clones. Furthermore, productive infection of peripheral T lymphocytes with simian immunodeficiency virus (SIV)?in vitro was confirmed by intracellular SIV p27 staining. This study could facilitate using Japanese macaques as models for human hematological and immunological disorders and infectious diseases. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译:</span><Abstract Type =“main”XML:ID =“JMP12460-ABS-0001”XML:Lang =“en”> <标题类型=“main”>抽象</ title> > 我们以日本猕三方特征( macaca fuscata </ i> )使用流式细胞术的造血细胞并鉴定了28个交叉反应性抗人抗体克隆。 此外,通过细胞内SIV P27染色证实了与Simian免疫缺陷病毒(SIV)的外周T淋巴细胞的生产感染。 本研究可以促进日本猕猴作为人类血液和免疫疾病和传染病的模型。 </ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-36449/'>《Journal of medical primatology》</a> <b style="margin: 0 2px;">|</b><span>2020年第2期</span><b style="margin: 0 2px;">|</b><span>共5页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Tsukamoto Tetsuo&option=202" target="_blank" rel="nofollow">Tsukamoto Tetsuo;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nakamura Katsuki&option=202" target="_blank" rel="nofollow">Nakamura Katsuki;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Okada Seiji&option=202" target="_blank" rel="nofollow">Okada Seiji;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Division of HematopoiesisKumamoto UniversityKumamoto Japan;</p> <p>Primate Research InstituteKyoto UniversityInuyama Japan;</p> <p>Division of HematopoiesisKumamoto UniversityKumamoto Japan;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/40383.html" title="灵长目">灵长目;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=acquired immunodeficiency syndrome&option=203" rel="nofollow">acquired immunodeficiency syndrome;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=CD4 + T lymphocytes&option=203" rel="nofollow">CD4 + T lymphocytes;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=hematopoietic progenitor cells&option=203" rel="nofollow">hematopoietic progenitor cells;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=monkey AIDS models&option=203" rel="nofollow">monkey AIDS models;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=simian immunodeficiency virus&option=203" rel="nofollow">simian immunodeficiency virus;</a> </p> <div class="translation"> 机译:获得的免疫缺陷综合征;CD4 + T淋巴细胞;造血祖细胞;猴子艾滋病模型;猿猴免疫缺陷病毒; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div 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CAO Xiaohong</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=曹小红&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,曹小红</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=GONG Xiaoping&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,GONG Xiaoping</a> <span> <a href="/conference-cn-66917/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 第五届全国矿田构造与深部找矿预测学术研讨会 </a> <span> <span> . 2018</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06130455050305.html">Isolation and characterization of a novel chimpanzee lentivirus, designated simian immunodeficiency virus isolate cpz-ant</a> <b>[P]</b> . <span> 外国专利: <!-- 美国专利: --> US5624795A </span> <span> . 1997-04-29</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:新型黑猩猩慢病毒(称为猿免疫缺陷病毒分离株cpz-ant)的分离和鉴定 </span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06130450902025.html">Purified polynucleotide, dna, vector, host cell, hybridoma cell line, monoclonal antibody, processes to produce exodus, to increase resistance to infection by human immunodeficiency virus (hiv), for treatment of human immunodeficiency virus (hiv) infection , for the protection of bone marrow progenitor cells against cytotoxic effects and for the treatment of myeloproliferative diseases, and the use of an exodus protein product.</a> <b>[P]</b> . <span> 外国专利: <!-- --> BR9707142A </span> <span> . 1999-12-28</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:纯化的多核苷酸,dna,载体,宿主细胞,杂交瘤细胞系,单克隆抗体,产生出埃及菌,增加对人类免疫缺陷病毒(hiv)的感染抵抗力的过程,用于治疗人类免疫缺陷病毒(hiv)感染,用于保护骨髓祖细胞具有抗细胞毒性作用并用于治疗骨髓增生性疾病的能力,以及出埃及蛋白质产品的用途。 </span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130415371341.html">Chimeric human immunodeficiency virus type 1 (HIV-1) with enhanced dendritic cell and macrophage tropism comprising the simian immunodeficiency virus (SIV) minimal Vpx packaging domain</a> <b>[P]</b> . <span> 外国专利: <!-- 美国专利: --> US9149519B2 </span> <span> . 2015-10-06</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:具有增强的树突状细胞和巨噬细胞嗜性的嵌合型1型人类免疫缺陷病毒(HIV-1),包含猿猴免疫缺陷病毒(SIV)最小Vpx包装域 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right 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