Fabrication of microfluidic paper-based analytical devices by filtration-assisted screen printing

摘要

Highlights?A novel technique,i.e.filtration-assisted screen printing, was demonstrated for fabrication of paper-based microfluidics at the ambient conditions.?“Bleeding” of polymer into the channel will affect the time of solution's wicking through the channel.?Glucose detection with concentrations ranging from 5 to 50?mM was performed and a linear correlation was obtained.AbstractIn recent years, the paper-based microfluidics has been gaining attention because it is regarded as an inexpensive tool for detection and analysis in biomedical applications and clinical settings. This report, for the first time, describes a relatively simple and fast method,i.e.filtration-assisted screen printing (FASP) that can produce microfluidic paper-based analytical devices (μPAD) at ambient condition with time for constructing the channel wall of fluidic channel as less as 30?s. The channel walls are constructed by the polymer retained