One Pot Four-Component Synthesis of Novel Substituted 2-Phenyl-4(3H) Quinazolinones Using Recyclable Nanocrystalline CuMnO3 Catalyst

摘要

In the present study, nanocrystalline mixed metal oxide, CuMnO3 catalyst have been synthesized by mechano-chemical method with green chemistry approach. The synthesized catalyst was characterized by analytical techniques including FTIR, XRD, SEM, TEM and BET surface area. The synthesized catalyst shows high surface area is 121.06 m~2/g with particle size 18 nm. The one pot four component synthesis of substituted 2-phenyl-4(3H) quinazolinone from the reaction of anthra-nilic acid, benzoyl chloride, hydrazine hydrate and substituted benzaldehyde in presence of CuMnO3 nanocatalyst has been carried out. It affords the corresponding products with high yield (76-95%) in very short reaction time. All the obtained products were characterized with ~1HNMR, ~(13)CNMR, FTIR and EIMS.