Synthesis of 7-O-alkyl or 7-O-acyl Derivatives of Naringenin and Apigenin

摘要

Naringenin and apigenin are natural flavonoids that differ structurally only by the presence or absence of a double bond between carbons 2 and 3(Fig.1).Flavonoids are secondary metabolites of plants and fungi,and are found in many foods,such as vegetables and fruits.Flavonoids have been reported to therapeutically benefit cardiovascular disease,cancer,and inflammation,among others,and have been well known for the prevention of oxidative stress in the human body.In addition,they are being studied as therapeutic agents for various diseases.