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Absorbable Mg surgical tack: Proof of concept & in situ fixation strength

机译:可吸收的mg外科粘性:概念证明&原位固定力量

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摘要

A prototype magnesium (Mg) surgical tack is tested comparatively against commercially available tacks made of titanium (ProTack(tm), Medtronic) and PLGA (AbsorbaTack(tm) Medtronic). The pull-out force is measured in situ in a lap-shear pull-out test, using porcine abdominal muscle tissue as a model. The Mg tack had a pull-out force comparable to those of the commercially available tacks. The majority of the Mg tacks also had a more ductile failure mode (i.e. the tacks deformed prior to failure), compared to the commercial tacks which pulled directly from the tissue with no deformation. The Mg tacks deformed as they were removed from the tissue, causing less damage to the tissue in the process. This is the first reported use of a Mg alloy in this application, and the proof of concept indicates that this is an area that deserves further interest and study.
机译:对钛(Protack(TM),Medtronic)和PLGA(吸收(TM)Medtronic制成的商业上可用的粘性进行测试,对原型镁(Mg)手术粘性进行测试。 使用猪腹部肌肉组织作为模型,在搭接剪切拉出试验中以原位测量拉出力。 Mg Tack的拉出力与商业上可用的粘性相当。 大多数Mg钉钉也具有更具韧性的故障模式(即失败前变形的钉子),与直接从组织中拉出没有变形的商业粘性相比。 Mg Tackss在从组织中除去它们时变形,导致该过程中的组织损害较小。 这是第一次报道在本申请中使用MG合金,并且概念证明表明这是一个值得进一步的兴趣和研究的区域。

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