Fabrication of CaFe2O4/MoS2 hybrid and its application for adsorption of paclitaxel chemotherapy medication in injection vial and water samples

摘要

Non-modified molybdenum disulfide (MoS2) is known to adsorb various compounds. However, in case of very small particle sizes and high dispersibility, ordinary centrifugation and filtration fail to separate MoS2 from aqueous media limiting, its applicability to solid-phase extraction. To overcome this shortcoming, we have prepared a nanohybrid consisting of MoS2 and nanoparticles of CaFe2O4. Detailed characterizations through field emission scanning electron microscopy, vibrating sample magnetometer, X-ray diffraction and energy-dispersive X-ray techniques confirmed the formation of the hybrid. The adsorption behavior was systematically accessed through kinetic, equilibrium and thermodynamic experiments. The nanohybrid was applied to the adsorption of paclitaxel. The adsorption capacity was 68.96 mg g(-1). Also, the method was successfully applied to the preconcentration of the analytes in (spiked) injection vial of paclitaxel and water samples.