A facile and effective procedure for synthesis of polyfunctionalized pyrrolines from simultaneously stirring of carbon disulfide, aniline, arylglyoxals and beta-enaminocarbonyls

摘要

An efficient one-pot synthesis of 2H-pyrroline derivatives by a four-component reaction between carbon disulfide, aniline, arylglyoxals and beta-enaminocarbonyls in acetonitrile at room temperature under mild reaction conditions is reported. The addition reaction has been done to access broad range of 5-hydroxy-4-phenylcarbamodithioate 2-H pyrroline derivatives after about 6 h stirring. All reactions were performed in acetonitrile at room temperature. Reactions are clean, and products were isolated by simple filtration.