Determination of triazole fungicides in environmental water by magnetic solid-phase extraction coupled with UHPLC-MS/MS

摘要

A simple, rapid and environmentally friendly method was developed for the determination of triazole fungicides (TFs) in environmental water by magnetic solid-phase extraction coupled with UHPLC-MS/MS. The target analytes were quantitatively adsorbed on magnetic multi-wall carbon nanotubes (M-MWCNTs), and then magnetically isolated. After desorption with acetone, the spiked samples were analyzed by UHPLC-MS/MS under optimized conditions, which demonstrated good linearity between 0.04 and 500.0 mu gL(-1) with the correlation coefficient of 0.9992-0.9998, the limits of detection of 0.011-0.067 mu g L-1 and the limits of quantification of 0.037-0.224 mu g L-1.The accuracy of the proposed method was evaluated by measuring the recovery of the spiked samples, which ranged from 91.2 to 108.4% with the relative standard deviations from 1.0 to 7.5% for the spiked samples. The proposed method has been successfully applied to the determination of the target compounds in real environmental water samples. The results demonstrate that the developed method has great potential for the determination of TFs in water.