Organic base grafted on magnetic nanoparticles as a recoverable catalyst for the green synthesis of hydropyridine rings

摘要

Synthesis of 4-aminiquinaldine grafted on silica-coated nano-Fe3O4 particles (MNPs-AQ) and their performance as a retrievable heterogeneous basic catalyst are disclosed. The catalytic performance of this novel material was studied for the green synthesis of substituted 1,4-dihydropyridine and polyhydroquinoline derivatives via one-pot multicomponent reactions. Eco-friendly method, high yield and purity of the desired products, and short reaction time along with the ease of the work-up procedure outline the advantages of these new methodologies over the earlier ones. The surface and magnetic properties of the core/shell hybrid nanoparticles were characterized via TEM, SEM, XRD, EDS, and FT-IR analysis techniques. This nanocatalyst is recyclable without any deterioration in its catalytic activity.