Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD

Dyer Adam H.; Murphy Claire; Lawlor Brian; Kennelly Sean P.; Segurado Ricardo; Kennelly Sean; Rikkert Marcel G. M. Olde; Howard Robert; Pasquier Florence; Brjesson-Hanson Anne; Tsolaki Magda; Lucca Ugo; Molloy D. William; Coen Robert; Riepe Matthias W.; Kalman Janos; Kenny Rose Anne; Cregg Fiona; ODwyer Sarah; Walsh Cathal; Adams Jessica; Banzi Rita; Breuilh Laetitia; Daly Leslie; Hendrix Suzanne; Aisen Paul; Gaynor Siobhan; Sheikhi Ali; Taekema Diana G.; Verhey Frans R.; Nemni Raffaello; Nobili Flavio; Franceschi Massimo; Frisoni Giovanni; Zanetti Orazio; Konsta Anastasia; Anastasios Orologas; Nenopoulou Styliani; Tsolaki-Tagaraki Fani; Pakaski Magdolna; Dereeper Olivier; de la Sayette Vincent; Senechal Olivier; Lavenu Isabelle; Devendeville Agnes; Calais Gauthier; Crawford Fiona; Mullan Michael; Aalten Pauline; Berglund Maria A.; Claassen Jurgen A.; De Heus Rianne A.; De Jong Daan L. K.; Godefroy Olivier; Hutchinson Siobhan; Ioannou Aikaterini; Jonsson Michael; Kent Annette; Kern Jrgen; Nemtsas Petros; Panidou Minoa-Kalliopi; Abdullah Laila; Paris Daniel; Santoso Angelina M.; van Spijker Gerrita J.; Spiliotou Martha; Thomoglou Georgia; Wallin Anders

首页> 外文期刊>Journal of the American Medical Directors Association >Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD

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Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD

机译：长期苯并二氮杂卓和相关药物（BDZR）的认知结果在生活中的人们用轻度到中度阿尔茨海默病的人：尼尔维德的结果

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Objective: Benzodiazepines and related drugs (BDZRs) have been associated with an increased risk of Alzheimer's disease (AD) in later life. Despite this, it remains unclear whether ongoing BDZR use may further accelerate cognitive decline in those diagnosed with mild to moderate AD.

机译：目的：苯并二氮杂卓和相关药物（BDZRS）已与阿尔茨海默病（AD）在后期生命中增加的风险有关。尽管如此，它仍然尚不清楚正在进行的BDZR使用是否可以进一步加速认知的降低患有轻度至中度广告的人的认知下降。

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《Journal of the American Medical Directors Association 》 |2020年第2期| 共7页
作者
Dyer Adam H.; Murphy Claire; Lawlor Brian; Kennelly Sean P.; Segurado Ricardo; Kennelly Sean; Rikkert Marcel G. M. Olde; Howard Robert; Pasquier Florence; Brjesson-Hanson Anne; Tsolaki Magda; Lucca Ugo; Molloy D. William; Coen Robert; Riepe Matthias W.; Kalman Janos; Kenny Rose Anne; Cregg Fiona; ODwyer Sarah; Walsh Cathal; Adams Jessica; Banzi Rita; Breuilh Laetitia; Daly Leslie; Hendrix Suzanne; Aisen Paul; Gaynor Siobhan; Sheikhi Ali; Taekema Diana G.; Verhey Frans R.; Nemni Raffaello; Nobili Flavio; Franceschi Massimo; Frisoni Giovanni; Zanetti Orazio; Konsta Anastasia; Anastasios Orologas; Nenopoulou Styliani; Tsolaki-Tagaraki Fani; Pakaski Magdolna; Dereeper Olivier; de la Sayette Vincent; Senechal Olivier; Lavenu Isabelle; Devendeville Agnes; Calais Gauthier; Crawford Fiona; Mullan Michael; Aalten Pauline; Berglund Maria A.; Claassen Jurgen A.; De Heus Rianne A.; De Jong Daan L. K.; Godefroy Olivier; Hutchinson Siobhan; Ioannou Aikaterini; Jonsson Michael; Kent Annette; Kern Jrgen; Nemtsas Petros; Panidou Minoa-Kalliopi; Abdullah Laila; Paris Daniel; Santoso Angelina M.; van Spijker Gerrita J.; Spiliotou Martha; Thomoglou Georgia; Wallin Anders;
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作者单位

Tallaght Univ Hosp Dept Age Related Healthcare Dublin 24 Ireland;

Tallaght Univ Hosp Dept Age Related Healthcare Dublin 24 Ireland;

Trinity Coll Dublin Sch Med Dept Med Gerontol Dublin Ireland;

Tallaght Univ Hosp Dept Age Related Healthcare Dublin 24 Ireland;

Univ Coll Dublin CSTAR Dublin Ireland;

Tallaght Hosp Dept Age Related Healthcare Dublin 24 Ireland;

Radboudumc Donders Inst Med Neurosci Dept Geriatr Med Radboudumc Alzheimer Ctr Nijmegen;

UCL Div Psychiat London England;

Univ Lille DISTALZ Lab Excellence CHU Lille F-59000 Lille France;

Univ Gothenburg Sahlgrenska Acad Inst Neurosci &

Physiol Dept Psychiat &

Neurochem Gothenburg;

Papanikolaou Gen Hosp Thessaloniki Thessaloniki Greece;

IRCCS Ist Ric Farmacol Mario Negri Lab Geriatr Neuropsychiat Milan Italy;

Univ Coll Cork Ctr Gerontol &

Rehabil Cork Ireland;

St James Hosp Mercers Inst Res Ageing Dublin Ireland;

Ulm Univ BKH Gunzburg Dept Geriatr &

Old Age Psychiat Psychiat 2 Ulm Germany;

Univ Szeged Dept Psychiat Szeged Hungary;

Trinity Coll Dublin Dept Med Gerontol Dublin Ireland;

Trinity Coll Dublin Dept Med Gerontol Dublin Ireland;

St James Hosp Mercers Inst Res Ageing Dublin Ireland;

Univ Limerick Hlth Res Inst Limerick Ireland;

Kings Coll London Dept Old Age Psychiat London England;

IRCCS Ist Ric Farmacol Mario Negri Lab Geriatr Neuropsychiat Milan Italy;

Univ Lille DISTALZ Lab Excellence CHU Lille F-59000 Lille France;

Univ Coll Dublin CSTAR Dublin Ireland;

Pentara Corp 2180 Claybourne Ave Salt Lake City UT USA;

Univ Southern Calif Dept Neurol Los Angeles CA 90007 USA;

Mol Med Ireland Dublin Ireland;

Univ Limerick Hlth Res Inst Limerick Ireland;

Rijnstate Hosp Dept Geriatr Med Arnhem Netherlands;

Maastricht Univ Alzheimer Ctr Limburg Sch Mental Hlth &

Neurosci Dept Psychiat &

Neuropsychol;

Univ Milan IRCCS Don Gnocchi Fdn Milan Italy;

Univ Genoa Dept Neurosci DINOGMI Genoa Italy;

Multimedica Neurol Dept Castellanza Italy;

Ctr San Giovanni di Dio IRCCS Fatebenefratelli Brescia Italy;

Ctr San Giovanni di Dio IRCCS Fatebenefratelli Brescia Italy;

Aristotle Univ Thessaloniki AUTH Papageorgiou Gen Hosp Psychiat Dept 1 Thessaloniki Greece;

Ahepa Univ Gen Hosp Thessaloniki Thessaloniki Greece;

Papanikolaou Gen Hosp Thessaloniki Thessaloniki Greece;

Papanikolaou Gen Hosp Thessaloniki Thessaloniki Greece;

Univ Szeged Dept Psychiat Szeged Hungary;

Ctr Hosp Calais Calais France;

CHU Caen Caen France;

Ctr Hosp Lens Lens France;

Ctr Hosp Bethune Bethune France;

CHU Amiens Amiens France;

GHICL Lille France;

Archer Pharmaceut Sarasota FL USA;

Archer Pharmaceut Sarasota FL USA;

Maastricht Univ Alzheimer Ctr Limburg Sch Mental Hlth &

Neurosci Dept Psychiat &

Neuropsychol;

Sahlgrens Univ Hosp Gothenburg Sweden;

Radboudumc Donders Inst Med Neurosci Dept Geriatr Med Radboudumc Alzheimer Ctr Nijmegen;

Radboudumc Donders Inst Med Neurosci Dept Geriatr Med Radboudumc Alzheimer Ctr Nijmegen;

Radboudumc Donders Inst Med Neurosci Dept Geriatr Med Radboudumc Alzheimer Ctr Nijmegen;

CHU Amiens Amiens France;

St James Hosp Dublin Ireland;

Aristotle Univ Thessaloniki Ahepa Univ Gen Hosp Dept Neurol 1 Thessaloniki Greece;

Univ Gothenburg Sahlgrenska Acad Inst Neurosci &

Physiol Dept Psychiat &

Neurochem Gothenburg;

Trinity Coll Dublin Dublin Ireland;

Univ Gothenburg Sahlgrenska Acad Inst Neurosci &

Physiol Dept Psychiat &

Neurochem Gothenburg;

Aristotle Univ Thessaloniki Ahepa Univ Gen Hosp Dept Neurol 1 Thessaloniki Greece;

Aristotle Univ Thessaloniki Ahepa Univ Gen Hosp Dept Neurol 1 Thessaloniki Greece;

Roskamp Inst Sarasota FL USA;

Roskamp Inst Sarasota FL USA;

Radboudumc Donders Inst Med Neurosci Dept Geriatr Med Radboudumc Alzheimer Ctr Nijmegen;

Radboudumc Donders Inst Med Neurosci Dept Geriatr Med Radboudumc Alzheimer Ctr Nijmegen;

Aristotle Univ Thessaloniki Ahepa Univ Gen Hosp Dept Neurol 1 Thessaloniki Greece;

Aristotle Univ Thessaloniki Ahepa Univ Gen Hosp Dept Neurol 1 Thessaloniki Greece;

Univ Gothenburg Sahlgrenska Acad Inst Neurosci &

Physiol Dept Psychiat &

Neurochem Gothenburg;

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原文格式 PDF
正文语种 eng
中图分类预防医学、卫生学 ;
关键词
Dementia; benzodiazepines; cognition; benzodiazepines and related drugs;

机译：痴呆症;苯并二氮杂虫;认知;苯二氮卓和相关药物;

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专利

1. Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD [J] . Dyer Adam H., Murphy Claire, Lawlor Brian, Journal of the American Medical Directors Association . 2020 ,第2期

机译：长期苯并二氮杂卓和相关药物（BDZR）的认知结果在生活中的人们用轻度到中度阿尔茨海默病的人：尼尔维德的结果
2. Prescription of Benzodiazepines and Related Drugs in Patients with Mild Cognitive Deficits and Alzheimer's Disease [J] . Hessmann Philipp, Dodel Richard, Baum Erika, Pharmacopsychiatry . 2019 ,第2期

机译：苯二氮卓和相关药物的处方于轻度认知赤字和阿尔茨海默病的患者
3. INVESTIGATIONAL NEW ALZHEIMER’S DRUG TRICAPRILIN: POSSIBLE EFFECTS OF APOEε4 NON-CARRIER SELECTION AND SITE EFFECTS ON STUDY OUTCOMES IN A PHASE 2/3 STUDY IN MILD-TO-MODERATE ALZHEIMER’S DISEASE PATIENTS [J] . Samuel T. Henderson, Judith Walker, Michael Gold, Alzheimer’s & dementia: the journal of the Alzheimer’s Association . 2018 ,第7期

机译：Investigational新的Alzheimer的药物Tricaprilin：己酮4非载体选择的可能影响和现场对Mild-to-中等阿尔茨海默病患者的2/3研究中的研究结果的影响
4. Automatic Identification of Behavior Patterns in Mild Cognitive Impairments and Alzheimer's Disease Based on Activities of Daily Living [C] . Belkacem Chikhaoui, Maxime Lussier, Mathieu Gagnon, International conference on smart homes and health telematics . 2018

机译：基于日常生活活动的轻度认知障碍和阿尔茨海默氏病行为模式自动识别
5. Therapeutic recreation participation, cognitive functioning, and psychosocial well-being of skilled nursing facility residents diagnosed with mild or moderate Alzheimer's disease. [D] . Madori, Linda Levine. 2004

机译：被诊断患有轻度或中度阿尔茨海默氏病的熟练护理机构患者的治疗性娱乐参与，认知功能和心理社会幸福感。
6. Gait speed cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD [O] . Adam H. Dyer, Brian Lawlor, Sean P. Kennelly, 2020

机译：轻度至中度阿尔茨海默氏病患者的步态速度认知和跌倒：来自NILVAD的数据

Cognitive Outcomes of Long-term Benzodiazepine and Related Drug (BDZR) Use in People Living With Mild to Moderate Alzheimer's Disease: Results From NILVAD

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