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首页> 外文期刊>American Journal of Dermatopathology >Cholesterotic fibrous histiocytoma.
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Cholesterotic fibrous histiocytoma.

机译:胆固醇性纤维组织细胞瘤。

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摘要

Phrynoderma is a type of follicular hyperkeratosis located primarily on the extensor surfaces of the extremities. It is most commonly seen in Africa and Southeast Asia, where it is correlated with malnutrition; however, it is rare in developed countries, where it is often the result of malabsorption secondary to pancreatic insufficiency, colectomy, chronic giardiasis, and bariatric surgery. Here, we report a case of a 51-year-old white male patient, who presented to our Institute with a 1-year history of diffuse, reddish-brown asymptomatic papules associated with follicular nodules. In association with cutaneous symptomatology, the patient complained of also having night blindness. The patient, 4 years before, underwent a bariatric surgical treatment, which included a biliopancreatic diversion. Histologic examination of skin biopsy revealed hyperkeratosis and irregular acanthosis of the epidermis in association with dilated follicular infundibulum filled with keratinous material, whereas the laboratory investigations showed hypovitaminosis A. Based on the patient's history and cutaneous biopsy, a final diagnosis of phrynoderma was made. The steady increase of obesity in developed countries results in a relative increase in bariatric surgery. This must involve a multidisciplinary team to manage nutrition deficiencies and prevent possibly important complications, as mentioned in this report.
机译:毛囊皮病是一种滤泡性角化过度,主要位于四肢伸肌表面。它最常见于非洲和东南亚,与营养不良有关。然而,在发达国家很少见,这通常是由于胰腺功能不全,结肠切除术,慢性贾第鞭毛虫病和减肥手术继发的吸收不良所致。在这里,我们报告一例51岁的白人男性患者,该患者向我们研究所就诊,具有1年的弥漫性,红棕色无症状丘疹与滤泡性结节相关的病史。与皮肤症状有关,患者抱怨还患有夜盲症。该患者在4年之前接受了减肥手术,其中包括胆胰转移术。皮肤活检的组织学检查发现表皮过度角化和表皮不规则棘皮症伴有充填有角蛋白的扩张性滤泡漏斗,而实验室检查则显示维生素A缺乏。根据患者的病史和皮肤活检,可最终诊断出性皮病。发达国家肥胖症的持续增加导致减肥手术的相对增加。如本报告中所述,这必须由一个多学科团队来管理营养缺乏症并预防可能的重要并发症。

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