Primary Mucinous Carcinoma of the Skin: Usefulness of p63 in Excluding Metastasis and First Report of Psammoma Bodies

摘要

In the December 2007 issue, Breit-ing et al presented a case of primary mucinous carcinoma of the skin (PMCS), wherein they discussed establishing the primary site of the tumor.We recently observed a similar case of PMCS in a 68-year-old African black male who underwent excision of a polypoid skin-colored supraorbital mass. The tumor measured 64 X 38 X 32 mm and had a soft tan-white shiny gelatinous cut surface. Histology revealed typical features of PMCS including large regular lobules separated by thin fibrous septa, admixed with smaller cords of eccrine-like epithelial cells floating in abundant amorphous mucin. Lymphovascular invasion was seen, along with occasional psammoma bodies that were hitherto unreported in PMCS.