Extraction and determination of tricyclic antidepressants in real samples using air‐dispersed liquid–liquid microextraction prior to gas chromatography and flame ionization detection

Mofazzeli Farideh; Asaadi Shirvan Homeira; Mohammadi Fatemeh

摘要

Abstract >In the present research, a novel microextraction method was used based on dispersive liquid–liquid microextraction using low‐density solvent for the determination of trace amounts of amitriptyline and doxepin as model compounds in human plasma and spring water samples before gas chromatography and flame ionization detection. The parameters influencing the extraction efficiencies including type of the extracting solvent, volume of the aqueous sample solution (donor phase), volume of the extraction solvent (acceptor phase), the number of air‐injection, and the effects of pH and ionic strength were optimized. Under the optimized conditions, the obtained enrichment factors were >80. By plotting peak areas of the sample solutions versus various concentrations of the analytes, calibration curves were obtained which show the linear ranges of 10–3000?ng/mL with correlation coefficients of >0.996. The precision of the method was calculated <4.2 and the limit of detection was 1?ng/mL for two analytes. The proposed microextraction method was used for the extraction of the analytes in environmental water and plasma samples and the calculated relative recoveries were all >91%. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>摘要</标题> >在本研究中，基于分散液 - 液微萃取使用使用新型微萃取方法低密度溶剂，用于测定痕量的氨基百分之碱和白翅蛋白，作为气相色谱和火焰离子化检测的人血浆和弹簧水样中的模型化合物。影响提取效率的参数，包括提取溶剂的类型，水性样品水溶液（供体阶段）的体积，提取溶剂（受体相）的体积，空气喷射的数量和pH和离子强度的影响优化。在优化的条件下，获得的富集因子> 80。通过绘制样品溶液的峰面积与各种分析物的各种浓度，获得校准曲线，其显示为10-3000Ω·ng / ml的线性范围，具有> 0.996的相关系数。计算该方法的精度<4.2，两个分析物的检测极限为1〜Ng / ml。所提出的微萃取方法用于提取环境水和血浆样品中的分析物，并且计算的相对回收均为91％。</ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-35800/'>《Journal of separation science.》</a> <b style="margin: 0 2px;">|</b><span>2018年第23期</span><b style="margin: 0 2px;">|</b><span>共8页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mofazzeli Farideh&option=202" target="_blank" rel="nofollow">Mofazzeli Farideh;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Asaadi Shirvan Homeira&option=202" target="_blank" rel="nofollow">Asaadi Shirvan Homeira;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mohammadi Fatemeh&option=202" target="_blank" rel="nofollow">Mohammadi Fatemeh;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of ChemistryIslamic Azad UniversityQuchan Iran;</p> <p>Department of ChemistryIslamic Azad UniversityQuchan Iran;</p> <p>Department of ChemistryIslamic Azad UniversityQuchan Iran;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/159.html" title="化学">化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=amitriptyline&option=203" rel="nofollow">amitriptyline;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=doxepin&option=203" rel="nofollow">doxepin;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=gas chromatography&option=203" rel="nofollow">gas chromatography;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=microextraction&option=203" rel="nofollow">microextraction;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=sample preparation&option=203" rel="nofollow">sample preparation;</a> </p> <div class="translation"> 机译：amitiptyline;doxepin;气相色谱;微萃取;样品制备; </div> </li> </ul> </div> </div> <div class="literature cardcommon" id="literaturereference" style="display:none"> <div class="similarity "> <h3 class="all_title" id="enpatent111">引文网络</h3> <div class="referencetab clearfix"> <ul id="referencedaohang"> <li dataid="referenceul">参考文献</li> <li dataid="citationul">引证文献</li> <li dataid="commonreferenceul">共引文献</li> <li dataid="commoncitationul">同被引文献</li> <li dataid="tworeferenceul">二级参考文献</li> <li dataid="twocitationul">二级引证文献</li> </ul> </div> <div class="reference_details" id="referenceList"> <ul id="referenceul"></ul> <ul id="citationul"></ul> <ul id="commonreferenceul"></ul> <ul id="commoncitationul"></ul> <ul id="tworeferenceul"></ul> <ul id="twocitationul"></ul> </div> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025846512.html">Extraction and determination of tricyclic antidepressants in real samples using air‐dispersed liquid–liquid microextraction prior to gas chromatography and flame ionization detection</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mofazzeli Farideh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Mofazzeli Farideh,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Asaadi Shirvan Homeira&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Asaadi Shirvan Homeira,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mohammadi Fatemeh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Mohammadi Fatemeh </a> <a href="/journal-foreign-35800/" target="_blank" rel="nofollow" class="tuijian_authcolor">Journal of separation science. .</a> <span>2018</span><span>,第23期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：在气相色谱和火焰离子化检测之前使用空气分散液 - 液微萃取在真实样品中三环抗抑郁药的提取和测定</span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-foreign_detail_thesis/0204122401229.html">Development of Sodium Sulfate Induced Water Based Dispersive Liquid–Liquid Microextraction for the Extraction of Four Tricyclic Antidepressants in Urine Samples Prior to Their Determination by Gas Chromatography–Mass Spectrometry</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ali Mohebi&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ali Mohebi,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mir Ali Farajzadeh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Mir Ali Farajzadeh,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Abolghasem Jouyban&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Abolghasem Jouyban,</a> <a href="/journal-foreign-29146/" target="_blank" rel="nofollow" class="tuijian_authcolor">Pharmaceutical sciences. .</a> <span>2021</span><span>,第1期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过气相色谱 - 质谱法测定硫酸钠诱导水基分散液微萃取尿液中四三环抗抑郁药的诱导</span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/07040286929.html">Determination of three antidepressants in urine using simultaneous derivatization and temperature-assisted dispersive liquid-liquid microextraction followed by gas chromatography-flame ionization detection</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nabil Ali Akbar Alizadeh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Nabil Ali Akbar Alizadeh,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nouri Nina&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Nouri Nina,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Farajzadeh Mir Ali&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Farajzadeh Mir Ali </a> <a href="/journal-foreign-15039/" target="_blank" rel="nofollow" class="tuijian_authcolor">Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences .</a> <span>2015</span><span>,第7期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：同时衍生化和温度辅助分散液-液微萃取-气相色谱-火焰电离检测法测定尿液中三种抗抑郁药</span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-220287_thesis/020515874233.html">Application of Headspace Liquid-Phase Microextraction Using Ionic Liquid as Extractant Combined with Gas Chromatography-Hydrogen Flame Ionization Detector to the Determination of BTEXs in Water</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Huang Minghua&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Huang Minghua,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ma Xiaoguo&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ma Xiaoguo </a> <a href="/conference-foreign-220287/" target="_blank" rel="nofollow" class="tuijian_authcolor">Energy and Environment Technology, 2009. ICEET '09 .</a> <span>2009</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：离子液体萃取-气相色谱-氢火焰电离检测器顶空液相微萃取在水中BTEXs测定中的应用</span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-degree-foreign_mphd_thesis/02061784164.html">Determination of Polycyclic Aromatic Hydrocarbons (PAHs) in Water by Dispersive Liquid-Liquid Microextraction with Gas Chromatography-Mass Spectrometry (DLLME-GC-MS)</a> <b>[D] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ogunkunle, Emmanuel O.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ogunkunle, Emmanuel O. </a> <span>2018</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：分散液-液微萃取-气相色谱-质谱法（DLLME-GC-MS）测定水中的多环芳烃（PAHs）</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/04000914334.html">Determination of Two Antiepileptic Drugs in Urine by Homogenous Liquid-Liquid Extraction Performed in A Narrow Tube Combined with Dispersive Liquid-liquid Microextraction Followed by Gas Chromatography-flame Ionization Detection</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Behruz Feriduni&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Behruz Feriduni,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mir Ali Farajzadeh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Mir Ali Farajzadeh,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Abolghasem Jouyban&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Abolghasem Jouyban </a> <span>2019</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：窄管均相液液萃取-分散液-液微萃取-气相色谱-火焰电离检测联用测定尿中两种抗癫痫药</span> </p> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/01000124141297.html">Development of Sodium Sulfate Induced Water Based Dispersive Liquid–Liquid Microextraction for the Extraction of Four Tricyclic Antidepressants in Urine Samples Prior to Their Determination by Gas Chromatography–Mass Spectrometry</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ali Mohebi&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ali Mohebi,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mir Ali Farajzadeh&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Mir Ali Farajzadeh,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Abolghasem Jouyban&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Abolghasem Jouyban,</a> <span>2020</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过气相色谱 - 质谱法测定硫酸钠诱导水基分散液微萃取尿液中四三环抗抑郁药的诱导</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_food-fermentation-industries_thesis/020123164863.html">分散液液微萃取结合气相色谱-火焰光度检测器法测定芝麻香型白酒中3-甲硫基丙醇</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=唐晖慧&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 唐晖慧</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=金美东&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,金美东</a> <span> <a href="/journal-cn-9397/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 食品与发酵工业 </a> </span> <span> . 2016</span><span>,第005期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chemical-analysis-meterage_thesis/0201271835178.html">分散液液微萃取-气相色谱法测定地表水中三氯苯</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=于洪&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 于洪</a> <span> <a href="/journal-cn-11976/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 化学分析计量 </a> </span> <span> . 2019</span><span>,第001期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_detail_thesis/0201296523280.html">超声辅助-分散液液微萃取-气相色谱/质谱法测定葡萄酒中三唑类农药残留</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=郭亚芸&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 郭亚芸</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=丁燕&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,丁燕</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=韩晓梅&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,韩晓梅</a> <span> <a href="/journal-cn-57080/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 分析科学学报 </a> </span> <span> . 2018</span><span>,第3期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_physical-testing-chemical-analysis-part-bchemical-analysis_thesis/0201212449482.html">气相色谱-质谱法结合QuEChERS方法和分散液液微萃取技术测定茭白中三唑类农药残留</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=姚芳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 姚芳</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=宋志宇&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,宋志宇</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=聂晶&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,聂晶</a> <span> <a href="/journal-cn-7677/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 理化检验-化学分册 </a> </span> <span> . 2017</span><span>,第006期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-forensic-medicine_thesis/0201279328525.html">分散液液微萃取-气相色谱串联质谱联用法测定生物样品中艾司西酞普兰</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=管青林&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 管青林</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=解文凯&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,解文凯</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=吕晨曦&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,吕晨曦</a> <span> <a href="/journal-cn-293/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 法医学杂志 </a> </span> <span> . 2020</span><span>,第004期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-6185_thesis/020221625458.html">超声辅助分散液液微萃取快速测定液体样品中的四溴双酚A及其衍生物</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王雪梅&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王雪梅</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘稷燕&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,刘稷燕</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=江桂斌&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,江桂斌</a> <span> <a href="/conference-cn-6185/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 第七届全国环境化学学术大会 </a> <span> <span> . 2013</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020314304793.html">分散液液微萃取-气相色谱-质谱联用法测定丙二醇中痕量有机化合物</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=段书予&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 段书予</a> <span> . 2015</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06120106885484.html">分散液液微萃取结合磁固相萃取测定茶叶中三嗪类农药残留量方法</a> <b>[P]</b> . <span> 中国专利： CN102706993A </span> <span> . 2012-10-03</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120101578582.html">基于微波破乳分散液液微萃取和QuEChERS技术测定蔬菜中三唑类农药残留的方法</a> <b>[P]</b> . <span> 中国专利： CN110632226A </span> <span> . 2019-12-31</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130407384928.html">Method for metabolomic sample preparation based on ionic liquid dispersive liquid-liquid microextraction</a> <b>[P]</b> . <span> 外国专利：  US10012574B2 </span> <span> . 2018-07-03</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：基于离子液体分散液-液微萃取的代谢组学样品制备方法 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130418419490.html">METHOD FOR METABOLOMIC SAMPLE PREPARATION BASED ON IONIC LIQUID DISPERSIVE LIQUID-LIQUID MICROEXTRACTION</a> <b>[P]</b> . <span> 外国专利：  US2014273080A1 </span> <span> . 2014-09-18</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：离子液体分散液-液微萃取的代谢组学样品制备方法 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130406561184.html">QUICK METHOD FOR DETERMINING ORGANOMETALLIC COMPOUNDS IN ULTRA-TRACES, FROM SOIL SAMPLES, BY ULTRASONIC EXTRACTION-HEADSPACE-SOLID PHASE MICROEXTRACTION AND GAS CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETRY (): SURFACE WATER, SOIL, AIR, VEGETATION</a> <b>[P]</b> . <span> 外国专利：  RO132682A2 </span> <span> . 2018-06-29</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：超声萃取-顶空固相微萃取-质谱联用气相色谱法快速测定土壤样品中痕量有机物的快速方法（）：地表水，土壤，空气，植被 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" onclick="ywcd('0704025846512','4',7,2,1,'',this,24)" class="delivery" prompt="010401" title="通过人工服务将文献原文发送至邮箱" >获取原文</div> <div class="journalsub-pop-up" style="display: none"> <div class="journal-sub"> <h2>期刊订阅</h2> <img src="https://cdn.zhangqiaokeyan.com/img/loginclose.png" alt="关闭" onclick="$('.journalsub-pop-up').hide()"> <p class="pardon">抱歉，该期刊暂不可订阅，敬请期待！</p> <p class="current">目前支持订阅全部北京大学中文核心（2020）期刊目录。</p> <div style="display: flex;margin-top: 69px;justify-content: space-between;"> <div class="no-sub" onclick="$('.journalsub-pop-up').hide()">暂不订阅</div> <div class="other-sub" onclick="continueSub('from=pc-detail')">继续订阅其他期刊</div> </div> </div> </div> <div class="right_btn"> <ul> <li class="gouwuche">  </li> <li class="yijian"> <a href="javascript:void(0);" onclick="link_analysis('/mycenter/auth/complaint.html',this)" title="意见反馈">意见反馈</a> </li> <li class="top"> <a href="javascript:scrollTo(0,0);" title="回到顶部">回到顶部</a> </li> <li class="shouye"> <a href="/" title="首页">回到首页</a> </li> </ul> </div> <div class="xllindexfooter"> <div class="xllindexfootercenter"> <div class="xllindexfooterleft left" > <div class="xllindexfooterleftli"> <ul> <li><a href="/about.html" title="关于掌桥">关于掌桥</a></li> <li><a href="/help/helpmap.html" title="资源导航">资源导航</a></li> <li><a href="/help/helpguide.html" title="新手指南">新手指南</a></li> <li><a href="/help/helpcenter.html" title="常见问题">常见问题</a></li> <li><a href="/sitemap.html" title="网站地图">网站地图</a></li> <li><a href="/help/helpcenter.html?type=9" title="版权声明">版权声明</a></li> </ul> </div> <div class="xllindexfooterleft"> <p class="xllindexfooterlefteamil">客服邮箱：kefu@zhangqiaokeyan.com</p> <div class="xllindexfooterlefttcp"> <div class="xllindexfooterpoliceiimg"></div> <div class="xllindexfooterpoliceispan"> <span>京公网安备：11010802029741号 </span> <span>ICP备案号：<a href="https://beian.miit.gov.cn" rel="nofollow" target="_blank" title="ICP备案号">京ICP备15016152号-6</a></span> <span>六维联合信息科技 (北京) 有限公司©版权所有</span> </div> </div> </div> </div> <div class="xllindexfooterright left"> <ul> <li> <p style="font-weight: bold;">客服微信</p> <div></div> </li> <li> <p style="font-weight: bold;">服务号</p> <div></div> </li> </ul> </div> </div> </div> <span id="0704025846512down" data-source="7," data-out-id="mJiY9W8HsVx+tuy4Or6LelZoRDdNU9Wox8RJXVFscDwMSkwMsmy7e3fiBSHihQ9c," data-f-source-id="7" data-title="Extraction and determination of tricyclic antidepressants in real samples using air‐dispersed liquid–liquid microextraction prior to gas chromatography and flame ionization detection" data-price="20" data-site-name="" data-transnum="24" style="display:none;"></span> <input type="hidden" value="4" id="sourcetype"> <input type="hidden" value="0704025846512" id="docid"> <input type="hidden" value="35800" id="journalid"> <input type="hidden" value="1" id="inyn_provide_service_level"> <input type="hidden" value="https://cdn.zhangqiaokeyan.com" id="imgcdn"> <input type="hidden" value="1" id="isdeatail"> <input type="hidden" value="" id="syyn_indexed_database"> <input type="hidden" value="" id="servicetype"> <input type="hidden" id="pagename" value="Extraction and determination of tricyclic antidepressants in real samples using air‐dispersed liquid–liquid microextraction prior to gas chromatography and flame ionization detection"/> <input type="hidden" value="thesis_get_original" id="pageIdentification"> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/jquery-1.12.4.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/lwlh_ajax.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/zq.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/common.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/jquery.cookie.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/top.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/tip.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/login.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/down.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/search.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/newmail.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/page.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/searchtype.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/user/regist.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/zxs_solor/detail.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/zxs_solor/reference.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/statistics/static/pagecollection.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/tj.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/sse.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/pushbaidu.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/common/history.js"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/util/cookie.js?v=5.8.7"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/js/weipu/weipu.js?v=5.8.7"></script> </body> <script> function kefu(customization) { var from = GetQueryString("from"); if (from == null || from == "") { from = "other"; } var url = getWxWorkQrCode(73, from, customization); if (url == "" || typeof url == 'undefined') { url = "https://wework.qpic.cn/wwpic/994838_0LUTS-VqR0quT1N_1675665967/0"; } tipDocGuidance(url, '人工辅助获取外文期刊材料'); } $(function(){ var weiPuStatus = getCookie('WeiPuStatus'); if(weiPuStatus){ tipWeiPuStatus(weiPuStatus); delCookie('WeiPuStatus'); } getFacetKeywordVoInId(); var sourcetype = $("#sourcetype").val(); var inyn_provide_service_level = $("#inyn_provide_service_level").val(); if((sourcetype ==1||sourcetype==4)&&inyn_provide_service_level!=4){ getJournal(); } }) function toCoverPage(){ var sourcetype=$("#sourcetype").val var fromStr=""; if(sourcetype==0){ fromStr="pc-wwoaxiangqing"; } if(sourcetype==4){ fromStr="pc-wwdetail-title"; } if(sourcetype==5){ fromStr="pc-wwhuiyixiangqing"; } window.location.href=url+"/zhichengpingshenlunwen.html?from="+fromStr; } </script> </html>