首页> 外文期刊>Journal of separation science. >Comprehensive quality evaluation of the lateral root of Aconitum carmichaeliiAconitum carmichaelii Debx. (Fuzi): Simultaneous determination of nine alkaloids and chemical fingerprinting coupled with chemometric analysis
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Comprehensive quality evaluation of the lateral root of Aconitum carmichaeliiAconitum carmichaelii Debx. (Fuzi): Simultaneous determination of nine alkaloids and chemical fingerprinting coupled with chemometric analysis

机译:综合质量评价 aconitum carmichaelii的侧根 aconitum carmichaelii debx。 (富士):同时测定九种生物碱和化学指纹识别与化学计量分析相结合

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Abstract > Amino alcohol alkaloids are the active components in the lateral root of Aconitum carmichaelii Debx. (Fuzi), and they have a variety of pharmacological activities. However, the chemical fingerprints of the ester alkaloids reported to date were mainly obtained from high‐performance liquid chromatography coupled with ultraviolet detection, and it is difficult to obtain information about amino alcohol alkaloids in Fuzi from such chromatograms. In this paper, a comprehensive fingerprinting method was established using high‐performance liquid chromatography coupled with an evaporative light‐scattering detector for the simultaneous quantitative analysis of both the amino alcohol alkaloids and ester alkaloids. A total of 42 samples of Fuzi from four production areas were analyzed by constructing high‐performance liquid chromatography fingerprints. Then, the quantitative results of the chemical fingerprints combined with chemometrics methods were employed to reveal the factors affecting the geo‐authentic Fuzi and to determine characteristic components that can be used to identify these samples. The results indicated distinct differences in the alkaloid contents among samples from the four regions; the geographical origin may be the primary factor affecting the geo‐authentic Fuzi, and 15 major components (including songorine, neoline, and hypaconitine, which were quantitatively determined) were found to be characteristic components for the discrimination of Fuzi samples from various regions. Neoline might be a critical component for identifying geo‐authentic Fuzi. This approach is convenient, reproducible and provides a promising method for the quality evaluation of Fuzi. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译:</span><Abstract Type =“main”XML:Lang =“en”> <标题类型=“main”>摘录</标题> >氨基醇生物碱是 aconitum carmichaelii的侧根中的活性组分</我> debx。 (富士),他们有各种药理活动。然而,迄今为止报告的酯生物碱的化学指纹主要是从紫外检测偶联的高性能液相色谱中获得,并且难以从这种色谱图中获得有关富士氨基醇生物碱的信息。本文采用高效液相色谱法建立了综合指纹方法,其与蒸发光散射检测器偶联,用于同时定量分析氨基醇生物碱和酯生物碱。通过构建高性能液相色谱指纹,分析了来自四个生产区域的42个富子样本。然后,使用化学指纹与化学计量方法的定量结果用于揭示影响地理正品FUZI的因素,并确定可用于识别这些样品的特征组分。结果表明四个地区样品中生物碱含量明显差异;地理来源可能是影响地理正宗富士富子的主要因素,并且已发现15种主要成分(包括鸣脉,新碱和低质量)是从各个地区鉴别富士样品的特征组分。 Neoline可能是用于识别地理正品FUZI的关键组成部分。这种方法是方便,可再现的,并提供了富士岛质量评价的有希望的方法。 </ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-35800/'>《Journal of separation science.》</a> <b style="margin: 0 2px;">|</b><span>2019年第5期</span><b style="margin: 0 2px;">|</b><span>共11页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Luo Chunmei&option=202" target="_blank" rel="nofollow">Luo Chunmei;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yi Fanli&option=202" target="_blank" rel="nofollow">Yi Fanli;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xia Yanli&option=202" target="_blank" rel="nofollow">Xia Yanli;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Huang Zhifang&option=202" target="_blank" rel="nofollow">Huang Zhifang;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zhou Xianjian&option=202" target="_blank" rel="nofollow">Zhou Xianjian;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jin Xiaojun&option=202" target="_blank" rel="nofollow">Jin Xiaojun;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Tang Yina&option=202" target="_blank" rel="nofollow">Tang Yina;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yi Jinhai&option=202" target="_blank" rel="nofollow">Yi Jinhai;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia MedicaSichuan Academy of Chinese Medicine SciencesChengdu P. R. China;</p> <p>Sichuan Integrative Medicine HospitalChengdu P. R. China;</p> <p>Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia MedicaSichuan Academy of Chinese Medicine SciencesChengdu P. R. China;</p> <p>Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia MedicaSichuan Academy of Chinese Medicine SciencesChengdu P. R. China;</p> <p>Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia MedicaSichuan Academy of Chinese Medicine SciencesChengdu P. R. China;</p> <p>The First Affiliated Hospital of Zhejiang UniversityHangzhou P. R. China;</p> <p>Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia MedicaSichuan Academy of Chinese Medicine SciencesChengdu P. R. China;</p> <p>Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia MedicaSichuan Academy of Chinese Medicine SciencesChengdu P. R. China;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/159.html" title="化学">化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=amino alcohol alkaloids&option=203" rel="nofollow">amino alcohol alkaloids;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=fingerprinting&option=203" rel="nofollow">fingerprinting;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=geo‐authentic&option=203" rel="nofollow">geo‐authentic;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=quality evaluation&option=203" rel="nofollow">quality evaluation;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=traditional Chinese medicine&option=203" rel="nofollow">traditional Chinese medicine;</a> </p> <div class="translation"> 机译:氨基醇生物碱;指纹识别;地理正品;质量评价;中医; </div> </li> <li> <span class="lefttit">入库时间</span> <span>2022-08-20 10:07:45</span> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_traditional-chinese-medical-sciences_thesis/0201291441881.html">Clinical application of Aconitum carmichaelii Debx.(Fu Zi in Chinese)by traditional Chinese medicine physicians-A cross-sectional questionnaire survey in Beijing</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xiaopeng Zhao&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xiaopeng Zhao,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Shenglou Ni&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Shenglou Ni,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ning Liang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Ning Liang,</a> <a href="/journal-foreign-55120/" target="_blank" rel="nofollow" class="tuijian_authcolor">中医科学杂志(英文) .</a> <span>2021</span><span>,第004期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025846228.html">Comprehensive quality evaluation of the lateral root of <i >Aconitum carmichaeliiAconitum carmichaelii Debx. 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