Separation of no-carrier-added Ru-97 from B-11-induced Y target by encapsulation of Ru-97 into calcium alginate hydrogel beads

摘要

Ru-97 radioisotope, a promising candidate for radiopharmaceutical applications was produced by Y-nat(B-11,3n) Ru-97 reaction with 40 MeV projectile energy. Calcium alginate (CA) hydrogel beads, an environmentally benign matrix, were used for separation of no-carrier-added (NCA) Ru-97 from the bulk yttrium target through adsorption-desorption experiments with a high separation factor (S (Ru/Y) = 2.6 x 10(4)). It was also possible to encapsulate high purity Ru-97 in CA hydrogel beads.