Recommended nuclear data for medical radioisotope production: diagnostic positron emitters

摘要

An IAEA coordinated research project that began in 2012 and ended in 2016 was primarily dedicated to the compilation, evaluation and recommendation of cross-section data for the production of medical radionuclides. One significant part of this work focused on diagnostic positron emitters. These particular studies consist of 69 reactions for direct and indirect or generator production of Sc-44(Ti-44), Mn-52m(Fe-52), Mn-52g, Co-55, Cu-61, Cu-62(Zn-62), Ga-66, Ga-68(Ge-68), As-72(Se-72), Se-73, Br-76, Rb-82(Sr-82), Rb-82m, Y-86, Zr-89, Nb-90, Tc-94m, In-110m(Sn-110), Sb-118(Te-118), I-120, I-122(Xe-122), Cs-128(Ba-128), and Pr-140(Nd-140) medical radionuclides. The resulting reference cross-section data were obtained from Pade fits to selected and corrected experimental data, and integral thick target yields were subsequently deduced. Uncertainties in the fitted results were estimated via a Pade least-squares method with the addition of a 4% assessed systematic uncertainty. Experimental data were also compared with theoretical predictions available from the TENDL-2015 and TENDL-2017 libraries. All of the numerical reference cross-section data with their corresponding uncertainties and deduced integral thick target yields are available on-line at the IAEA-NDS medical portal www-nds.iaea.org/medicalportal and also at the IAEA-NDS web page www-nds.iaea.org/medical/positron_emitters.html.