Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors

Yu Mingdong; Su Baohui; Zhang Xiaoxia

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Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors

机译：栀子植物通过调节P2X3和P2X7受体来抑制大鼠慢性收缩损伤模型的疼痛

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摘要

Objectives: Here, using rat model, we investigated the roles of gardenoside in the chronic constriction injury (CCI) of the ischiadic nerve.

机译：目的：在这里，使用大鼠模型，我们调查了栀子苷在甲基审核神经的慢性收缩损伤（CCI）中的作用。

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来源
《Journal of receptor and signal transduction research》 |2018年第6期|共6页
作者
Yu Mingdong; Su Baohui; Zhang Xiaoxia;
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作者单位

Weifang People Hosp Dept Spine Surg 2 151 Guangwen St Kuiwen Dist 261041 Weifang Peoples R China;

Weifang People Hosp Dept Spine Surg 2 151 Guangwen St Kuiwen Dist 261041 Weifang Peoples R China;

Weifang People Hosp Dept Spine Surg 2 151 Guangwen St Kuiwen Dist 261041 Weifang Peoples R China;

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正文语种 eng
中图分类细胞形态学;
关键词
Gardenoside; ischiadic nerve chronic constriction injury; P2X3; P2X7; inflammation;

机译：栀子苷;甲状腺神经慢性收缩损伤;p2x3;p2x7;炎症;

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专利

1. Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors [J] . Yu Mingdong, Su Baohui, Zhang Xiaoxia Journal of receptor and signal transduction research . 2018,第1a6期

机译：栀子植物通过调节P2X3和P2X7受体来抑制大鼠慢性收缩损伤模型的疼痛
2. Botulinum toxin type A promotes microglial M2 polarization and suppresses chronic constriction injury-induced neuropathic pain through the P2X7 receptor [J] . Xianwei Gui, Hansen Wang, Lanxiang Wu, Cell & Bioscience . 2020,第1期

机译：肉毒杆菌毒素型A通过P2X7受体促进微胶质M2偏振并抑制慢性收缩损伤诱导的神经病疼痛
3. Pulsed radiofrequency inhibits expression of P2X3 receptors and alleviates neuropathic pain induced by chronic constriction injury in rats [J] . Miao Fu, Lan Meng, Hao Ren, 中华医学杂志（英文版） . 2019,第014期

机译：脉冲射频抑制P2X3受体的表达并减轻大鼠慢性压迫性损伤引起的神经性疼痛
4. P2X3 receptor mediates heat hyperalgesia in trigeminal neuropathic pain [C] . Shinoda M, Kawashima K, Ozaki N, International Congress on Neuropathic Pain . 2010

机译：P2X3受体在三叉神经病疼痛中介导热痛觉
5. The role of ionotropic glutamate receptors in chronic central pain after spinal cord injury [D] . Tan, Huaiyu 2007

机译：离子型谷氨酸受体在脊髓损伤后慢性中枢性疼痛中的作用
6. Botulinum toxin type A promotes microglial M2 polarization and suppresses chronic constriction injury-induced neuropathic pain through the P2X7 receptor [O] . Xianwei Gui, Hansen Wang, Lanxiang Wu, 2020

机译：A型肉毒杆菌毒素通过P2X7受体促进小胶质细胞M2极化并抑制慢性收缩损伤引起的神经性疼痛
7. Gardenoside combined with ozone inhibits the expression of P2X3 and P2X7 purine receptors in rats with sciatic nerve injury [O] . Mingdong Yu, Yong Zhao, Xiaoxia Zhang 2018

机译：栀子结合臭氧抑制了坐骨神经损伤大鼠P2x3和P2x7嘌呤受体的表达

Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors

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