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首页> 外文期刊>Alimentary pharmacology & therapeutics. >Natural history of acute colonic diverticular bleeding: a prospective study in 133 consecutive patients.
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Natural history of acute colonic diverticular bleeding: a prospective study in 133 consecutive patients.

机译:急性结肠憩室出血的自然史:连续133例患者的前瞻性研究。

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BACKGROUND: Bleeding recurrence rate after spontaneous haemostasis of colonic diverticular haemorrhage varies in the literature, and a small minority of patients will require endoscopic, radiological or surgical intervention. AIM: To study the natural history of colonic diverticular bleeding in consecutive patients. METHODS: We studied prospectively consecutive patients admitted for colonic diverticular bleeding from 1997 to 2005. Data on age, gender, 30-day mortality, therapeutic modality for bleeding management and subsequent rebleeding were collected. RESULTS: One hundred and thirty-three patients (mean age 75.7 years) were recruited. Bleeding stopped spontaneously in 123 patients (92.4%). A more interventional approach was necessary in 10 patients. Thirty-day mortality rate for first bleeding was 2.25%. Out of the 123 patients managed conservatively and submitted to an average follow-up of 47.5 months, 17 (13.8%) presented at least one recurrent diverticular bleeding. Spontaneous haemostasis was obtained in all recurrent cases except one, who died. The estimated bleeding recurrence rate was 3.8% at 1 year, 6.9% at 5 years and 9.8% at 10 years. CONCLUSIONS: The low estimated rebleeding rate and the fact that rebleeding can be treated conservatively in most cases suggest that an aggressive approach with intervention is not justified.
机译:背景:结肠憩室出血自发止血后的复发率在文献中有所不同,少数患者需要内镜,放射或手术干预。目的:研究连续患者结肠憩室出血的自然史。方法:我们研究了1997年至2005年连续接受结肠憩室出血的前瞻性患者。收集了有关年龄,性别,30天死亡率,出血治疗方法和随后再出血的数据。结果:招募了133例患者(平均年龄75.7岁)。 123例患者(92.4%)自发停止出血。 10例患者需要采取更多干预措施。首次出血的30天死亡率为2.25%。保守治疗并平均随访47.5个月的123例患者中,有17例(13.8%)至少发生了一次反复的憩室出血。除一名死亡病例外,所有复发病例均获得了自发止血作用。估计的1年出血复发率为3.8%,5年为6.9%,10年为9.8%。结论:估计的再出血率低,并且在大多数情况下可以保守治疗再出血的事实表明,采取积极的干预措施是不合理的。

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