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Review of current understanding of post-traumatic osteoarthritis resulting from sports injuries

机译:审查当前对运动损伤产生的创伤后骨关节炎的理解

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摘要

Certain types of joint injuries, common in athletes, are known to have a high association with the development of osteoarthritis (OA). Post-traumatic osteoarthritis (PTOA) is especially debilitating due to its earlier onset than traditional OA, and its predisposition to affect a younger and more active population. Five common athletic injuries have been demonstrated to be risk factors for the development of OA. These include ACL rupture, meniscus tear, glenohumeral instability, patellar dislocation, and ankle instability. Though the mechanisms responsible for the development of PTOA are not entirely clear, certain kinematic, biologic, and mechanical factors have been implicated. In addition, there has been an increased emphasis on development of new methods to detect early OA changes in patients with known risk factors, as early intervention may prevent the development of end-stage OA. New imaging modalities as well as the identification of specific biomarkers may allow earlier detection. Though these developments hold promise, it is not entirely known what steps we can take today to prevent the future development of OA, even with early detection. (c) 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:397-405, 2017.
机译:众所周知,某些类型的关节损伤,常见于运动员,与骨关节炎(OA)的发育具有很高的关联。由于其早期的发病,创伤后骨关节炎(PTOA)尤其比传统OA,以及影响更年轻,更活跃的人群的易感性。已经证明了五种常见的运动伤害是OA发展的危险因素。这些包括ACL破裂,弯月面撕裂,Glenohumal不稳定性,髌骨位错,踝关节不稳定。虽然负责PTOA的发展的机制并不完全清楚,但涉及某些运动,生物学和机械因素。此外,由于早期干预可能会阻止最终阶段OA的发展,提高了检测已知风险因素的早期OA变化的新方法的新方法的强调。新的成像模态以及特定生物标志物的识别可以稍前检测。虽然这些发展拥有承诺,但它并不完全知道我们今天可以采取哪些步骤,以防止未来OA的发展,即使是早期发现。 (c)2016骨科研究会。由Wiley期刊出版,Inc.J Orthop Res 35:397-405,2017。

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