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Method for quantitative assessment of acetabular bone defects

机译:定量评估髋臼骨缺损的方法

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ABSTRACT The objective of the study was to suggest a novel quantitative assessment of acetabular bone defects based on a statistical shape model, validate the method, and present preliminary results. Two exemplary CT‐data sets with acetabular bone defects were segmented to obtain a solid model of each defect pelvis . The pathological areas around the acetabulum were excluded and a statistical shape model was fitted to the remaining healthy bone structures. The excluded areas were extrapolated such that a solid model of the native pelvis per specimen resulted (i.e., each pelvis without defect). The validity of the reconstruction was tested by a leave‐one‐out study. Validation results showed median reconstruction errors of 3.0?mm for center of rotation, 1.7?mm for acetabulum diameter, 2.1° for inclination, 2.5° for anteversion, and 3.3?mm 3 for bone volume around the acetabulum. By applying Boolean operations on the solid models of defect and native pelvis , bone loss and bone formation in four different sectors were assessed. For both analyzed specimens, bone loss and bone formation per sector were calculated and were consistent with the visual impression. In specimen_1 bone loss was predominant in the medial wall (10.8?ml; 79%), in specimen_2 in the posterior column (15.6?ml; 46%). This study showed the feasibility of a quantitative assessment of acetabular bone defects using a statistical shape model‐based reconstruction method. Validation results showed acceptable reconstruction accuracy, also when less healthy bone remains. The method could potentially be used for implant development, pre‐clinical testing, pre‐operative planning, and intra‐operative navigation. ? 2018 The Authors. Journal of Orthopaedic Research ? Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 9999:1–9, 2018.
机译:摘要该研究的目的是基于统计形状模型,验证方法,验证方法,验证方法,验证方法。将具有髋臼骨缺陷的两个示例性CT数据组分段以获得每个缺陷骨盆的固体模型。排除髋臼周围的病理区域,统计形状模型适用于剩余的健康骨结构。将排斥的区域推断为使得每样标本的天然骨盆的固体模型得到(即,每个骨盆没有缺陷)。重建的有效性是通过休假研究来测试的。验证结果表明,旋转中心的中值重建误差为3.0Ωmm,1.7Ω·mm,用于髋臼直径为2.1°,倾角为2.5°,3.3Ω·mm 3,髋臼周围的骨骼体积。通过对缺陷和天然骨盆的固体模型应用布尔操作,评估四个不同部门的骨质损失和骨形成。对于分析的标本,计算每种部门的骨质损失和骨形成,并与视觉印象一致。在样本_1骨损失中,在后柱中的壁上(10.8×ml; 79%)中的主要损失是主要的(15.6μl; 46%)。该研究表明,使用统计形状模型的重建方法显示髋臼骨缺陷的定量评估的可行性。验证结果显示出可接受的重建准确性,而且在较不健康的骨骼仍然存在时。该方法可能用于植入物开发,临床前测试,术前规划和术中导航。还2018年作者。骨科研究杂志?由Wiley Hearyicals,Inc。代表骨科研究会出版。 J Orthop Res 9999:1-9,2018。

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