A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial)

Stuerner Klarissa Hanja; Stellmann Jan-Patrick; Doerr Jan; Paul Friedemann; Friede Tim; Schammler Sven; Reinhardt Stefanie; Gellissen Susanne; Weissflog Gainet; Faizy Tobias Djamsched; Werz Oliver; Fleischer Sabine; Vaas Lea A. I.; Herrmann Frank; Pless Ole; Martin Roland; Heesen Christoph

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A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial)

机译：标准化的乳香萃取液降低了复发延迟多发性硬化症（SABA IIA IIA试验）中的疾病活动

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Objective To investigate whether oral administration of a standardised frankincense extract (SFE) is safe and reduces disease activity in patients with relapsing-remitting multiple sclerosis (RRMS).

机译：目的探讨是否探讨了标准化的乳香萃取物（SFE）的口服给药是安全的，并减少复发延迟多发性硬化症（RRMS）的患者疾病活动。

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来源
《Journal of Neurology, Neurosurgery and Psychiatry》 |2018年第4期|共9页
作者
Stuerner Klarissa Hanja; Stellmann Jan-Patrick; Doerr Jan; Paul Friedemann; Friede Tim; Schammler Sven; Reinhardt Stefanie; Gellissen Susanne; Weissflog Gainet; Faizy Tobias Djamsched; Werz Oliver; Fleischer Sabine; Vaas Lea A. I.; Herrmann Frank; Pless Ole; Martin Roland; Heesen Christoph;
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作者单位

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Charite NeuroCure Clin Res Ctr Berlin Germany;

Charite NeuroCure Clin Res Ctr Berlin Germany;

Univ Med Ctr Gottingen Dept Med Stat Gottingen Germany;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Univ Klinikum Hamburg Eppendorf Dept Diagnost &

Intervent Neuroradiol Hamburg Germany;

Friedrich Schiller Univ Inst Pharm Dept Pharmaceut &

Med Chem Jena Germany;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

Fraunhofer IME Screening Port Hamburg Germany;

Evotec AG Hamburg Germany;

Fraunhofer IME Screening Port Hamburg Germany;

Univ Hosp Zurich Dept Neurol Neuroimmunol &

MS Res Sect Zurich Switzerland;

Univ Med Ctr Hamburg Eppendorf Ctr Mol Neurobiol Hamburg Inst Neuroimmunol &

Multiple Sclerosis;

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正文语种 eng
中图分类神经病学;
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专利

1. A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial) [J] . Stuerner Klarissa Hanja, Stellmann Jan-Patrick, Doerr Jan, Journal of Neurology, Neurosurgery and Psychiatry . 2018,第4期

机译：标准化的乳香萃取液降低了复发延迟多发性硬化症（SABA IIA IIA试验）中的疾病活动
2. Serum Levels of Anti-Myelin Antibodies in Relapsing-Remitting Multiple Sclerosis Patients during Different Phases of Disease Activity and Immunomodulatory Therapy [J] . FrancescoAngelucci, MassimilianoMirabella, GiovanniFrisullo, Disease markers . 2005,第2期

机译：反复发作的多发性硬化症患者在疾病活动和免疫调节治疗不同阶段的血清抗髓磷脂抗体水平
3. Peginterferon beta-1a improves MRI measures and increases the proportion of patients with no evidence of disease activity in relapsing-remitting multiple sclerosis: 2-year results from the ADVANCE randomized controlled trial [J] . Douglas L. Arnold, Peter A. Calabresi, Bernd C. Kieseier, BMC Neurology . 2017,第1期

机译：Peginterferon beta-1a改善了MRI测量并增加了复发-缓解型多发性硬化症中无疾病活动证据的患者比例：ADVANCE随机对照试验的2年结果
4. Microstructural Modulations in the Hippocampus Allow to Characterizing Relapsing-Remitting Versus Primary Progressive Multiple Sclerosis [C] . Lorenza Brusini, Ilaria Boscolo Galazzo, Muge Akinci, International Workshop on Brain-Lesion;Medical Image Computing and Computer Assisted Intervention Conference . 2020

机译：海马中的微观结构调制允许表征复发 - 延长与初级进步多发性硬化
5. Mesenchymal Stem Cell-derived Exosomes Ameliorate Disease in a Model of Relapsing-remitting Multiple Sclerosis [D] . Yuan, Oliver 2018

机译：间充质干细胞源性外来体改善复发-释放性多发性硬化症模型中的疾病。
6. Serum Levels of Anti-Myelin Antibodies in Relapsing-Remitting Multiple Sclerosis Patients during Different Phases of Disease Activity and Immunomodulatory Therapy [O] . Francesco Angelucci, Massimiliano Mirabella, Giovanni Frisullo, 2005

机译：反复发作的多发性硬化症患者在疾病活动和免疫调节治疗不同阶段的血清抗髓磷脂抗体水平
7. A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial) [O] . Klarissa Hanja Stürner, Jan-Patrick Stellmann, Jan Dörr, 2017

机译：标准化的乳香药物降低了复发延迟多发性硬化的疾病活动（SABA期IIA试验）

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial)

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