A principled multivariate intersubject analysis of generalized partial directed coherence with Dirichlet regression: Application to healthy aging in areas exhibiting cortical thinning

摘要

Background Generalized Partial Directed Coherence (GPDC) is a multivariate measure of predictability between functional timeseries defined in the frequency domain. However, analysis has often been constrained by its compositional nature. Specifically, the squared GPDC from a node region to all nodes in any given frequency must sum to one.