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首页> 外文期刊>American Journal of Biochemistry and Biotechnology >Phytochemical and pharmacological evaluation of selected plants.
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Phytochemical and pharmacological evaluation of selected plants.

机译:选定植物的植物化学和药理学评估。

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摘要

Araucaria cookii, Bauhinia blakeana and Brassaia actinophylla are ornamental plants. The presence of various phytochemicals and pharmacologically important compounds in these plants can be exploited for their medicinal use. But there are no reports on the phytochemical and pharmacological evaluation of these plants and this study aims at investigating these. The plant extracts were prepared in different solvents like methanol, ethanol, ethyl acetate, acetone, hexane, water and chloroform. Qualitative analysis of phytochemicals were assessed. The anti-microbial, anti-oxidant and enzyme inhibitory activity was determined for all three plant extracts. Anti-bacterial activity against three gram negative bacteria, E. coli, Pseudomonas and Klebsiella was done and Araucaria cooki showed highest antibacterial activity among the three plants. Maximum antioxidant activity was seen in methanol extract of Brassaia actinophyla with 81% inhibition. The order of the antioxidant activity of the three plants are in the order B. actinophylla > A. cookie > B. blakeana. The results of phytochemical analysis suggest that phytosteroids are present in all the three plants. Maximum inhibition against the tested enzymes was exhibited by hexane and chloroform extracts of A. cookii. Hemolytic activity was done and the hexane extract showed maximum haemolysis where as aqueous extracts showed minimum activity. From the results it is clear that the three plant extracts has pharmacological applications. This is the first report of antimicrobial, antioxidant and enzyme inhibitory activities of these three plant extracts. Further studies are needed to exploit the actual mechanism and active compounds of these plants.
机译:南洋杉,紫荆花和Brassaia actinophylla是观赏植物。这些植物中各种植物化学物质和重要的药理化合物的存在可用于其药用。但是,尚无有关这些植物的植物化学和药理评价的报道,本研究旨在调查这些植物。植物提取物是在不同的溶剂(如甲醇,乙醇,乙酸乙酯,丙酮,己烷,水和氯仿)中制备的。评估了植物化学物质的定性分析。测定了所有三种植物提取物的抗微生物,抗氧化和酶抑制活性。对三种革兰氏阴性细菌,大肠杆菌,假单胞菌和克雷伯菌进行了抗菌活性,南洋杉显示出这三种植物中最高的抗菌活性。在Brassia actinophyla的甲醇提取物中观察到最大的抗氧化活性,抑制率达81%。这三种植物的抗氧化活性的顺序为:猕猴桃>曲奇>番茄。植物化学分析的结果表明,所有三种植物中都存在植物类固醇。库克曲霉的己烷和氯仿提取物表现出对测试酶的最大抑制作用。进行了溶血活性,己烷萃取物显示出最大的溶血作用,而水萃取物显示出最小的溶血作用。从结果可以清楚地看出这三种植物提取物具有药理学应用。这是这三种植物提取物的抗微生物,抗氧化剂和酶抑制活性的首次报道。需要进一步研究以开发这些植物的实际机理和活性化合物。

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