Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement

摘要

This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility and the supporting scientific evidence. Explanations of the ratings and of the strength of overall evidence are given in Tables 1 and 2, respectively. The Research Gaps and Recommendations of Other Groups sections that are usually included in USPSTF recommendation statements are available in the complete recommendation statement on the USPSTF Web site at http://www.ahrq.gov/clinic/uspstf05/ brcagen/brcagenrs.htm. The complete information on which this statement is based,