Zr-89-immuno-PET and biodistribution preclinical studies to compare the tumor targeting of the novel anti-CD166 probody drug conjugate CX-2009 and its parental derivatives in a lung cancer xenograft mouse model.

Chomet Marion; Schreurs Maxime; Vasiljeva Olga; Nguyen Margaret; van Dongen Guus; Vugts Danielle

首页> 外文期刊>Journal of Labelled Compounds and Radiopharmaceuticals >Zr-89-immuno-PET and biodistribution preclinical studies to compare the tumor targeting of the novel anti-CD166 probody drug conjugate CX-2009 and its parental derivatives in a lung cancer xenograft mouse model.

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Zr-89-immuno-PET and biodistribution preclinical studies to compare the tumor targeting of the novel anti-CD166 probody drug conjugate CX-2009 and its parental derivatives in a lung cancer xenograft mouse model.

机译：ZR-89-免疫宠物和生物分布型临床前研究，比较新的抗CD166槲皮药物缀合物CX-2009的肿瘤靶向及其在肺癌异种移植小鼠模型中的父母衍生物。

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来源
《Journal of Labelled Compounds and Radiopharmaceuticals》 |2019年第s1期|共2页
作者
Chomet Marion; Schreurs Maxime; Vasiljeva Olga; Nguyen Margaret; van Dongen Guus; Vugts Danielle;
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作者单位

Vrije Univ Amsterdam Amsterdam UMC Radiol &

Nucl Med Amsterdam Netherlands;

Amsterdam UMC Amsterdam Netherlands;

CytomX Therapeut Inc San Francisco CA USA;

CytomX Therapeut Inc San Francisco CA USA;

Vrije Univ Amsterdam Med Ctr Amsterdam Netherlands;

Vrije Univ Amsterdam Amsterdam UMC Amsterdam Netherlands;

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原文格式 PDF
正文语种 eng
中图分类药学;
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入库时间 2022-08-20 09:30:08

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1. Zr-89-immuno-PET and biodistribution preclinical studies to compare the tumor targeting of the novel anti-CD166 probody drug conjugate CX-2009 and its parental derivatives in a lung cancer xenograft mouse model. [J] . Chomet Marion, Schreurs Maxime, Vasiljeva Olga, Journal of Labelled Compounds and Radiopharmaceuticals . 2019,第S1期

机译：ZR-89-免疫宠物和生物分布型临床前研究，比较新的抗CD166槲皮药物缀合物CX-2009的肿瘤靶向及其在肺癌异种移植小鼠模型中的父母衍生物。
2. Therapeutic Targeting of Golgi Phosphoprotein 2 (GOLPH2) with Armed Antibodies: A Preclinical Study of Anti-GOLPH2 Antibody Drug Conjugates in Lung and Colorectal Cancer Models of Patient Derived Xenografts (PDX) [J] . Liewen Heike, Markuly Norbert, Laeubli Heinz, Targeted oncology . 2019,第5期

机译：具有武装抗体的高尔基磷蛋白2（GOLPH2）的治疗靶向：肺癌和结直肠癌模型的抗GOLPH2抗体药物缀合物的临床前研究患者衍生的异种移植物（PDX）
3. Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase-overexpressing tumor xenograft model. [J] . Chau Y, Dang NM, Tan FE, Journal of pharmaceutical sciences. . 2006,第3期

机译：在基质-金属蛋白酶过表达的肿瘤异种移植模型中使用生物分布研究研究新型右旋糖酐-肽-甲氨蝶呤偶联物的靶向机制。
4. Development and Evaluation of CD44- Targeted Lipid-Based Nanoparticles in an Orthotopic Non-Small Cell Lung Cancer Xenograft Mouse Model [C] . Amy E. Webster, J. Christopher Luft, Joseph M. DeSimone American Chemical Society Division of Polymeric Materials Science and Engineering Conference . 2015

机译：在原位非小细胞肺癌异种移植小鼠模型中CD44-靶向脂质基纳米粒子的发展与评价
5. Comparing gene expression profiles of cell culture models with profiles of tumor xenografts and patient tumors: Implications for lung and breast cancers. [D] . Creighton, Chad J. 2006

机译：将细胞培养模型的基因表达谱与异种移植瘤和患者肿瘤谱进行比较：对肺癌和乳腺癌的影响。
6. The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice [O] . Marion Chomet, Maxime Schreurs, Margaret Nguyen, 2020

机译：用89Zr-immuno-PET监测抗CD166 Probody药物偶联物CX-2009及其亲代衍生物的肿瘤靶向性能
7. Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody–Drug Conjugate in Patient-derived Xenografts [O] . Adnan O. Abu-Yousif, Donna Cvet, Melissa Gallery, 2020

机译：在患者衍生的异种移植物中新型抗GCC抗体 - 药物缀合物的临床前抗肿瘤活性和生物分布

Zr-89-immuno-PET and biodistribution preclinical studies to compare the tumor targeting of the novel anti-CD166 probody drug conjugate CX-2009 and its parental derivatives in a lung cancer xenograft mouse model.

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