Radiosynthesis of carbon 14 and tritium labeled potent neuraminidase inhibitors

Raja; S.; St George; K.; Fan; L.; Maring; C.; Mcdaniel; K.; Degoey; D.

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Radiosynthesis of carbon 14 and tritium labeled potent neuraminidase inhibitors

机译：碳14和氚标记有效神经氨酸酶抑制剂的可覆盖合成

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The carbon-~(14) label Neuraminidase Inhibitor 1, corresponding ethyl A and isopropyl B prodrugs, and the benchmark compound [ ~(14)C]GS4104 were prepared by using [14C]acetic anhydride. The tritium labeled ethyl A prodrug was prepared by using [~3H]methyl iodide. Copyright r 2010 John Wiley & Sons, Ltd.

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《Journal of Labelled Compounds and Radiopharmaceuticals》 |2010年第6期|共3页
作者
Raja; S.; St George; K.; Fan; L.; Maring; C.; Mcdaniel; K.; Degoey; D.;
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作者单位

AP9 Abbott Laboratories 100 Abbott Park IL 60064 United States;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
GS4104; Influenza virus; Neuraminidase inhibitors;

机译：GS4104;流感病毒;神经氨酸酶抑制剂;

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专利

1. Radiosynthesis of carbon 14 and tritium labeled potent neuraminidase inhibitors [J] . Raja, S., St George, Journal of Labelled Compounds and Radiopharmaceuticals . 2010,第5a6期

机译：碳14和tri标记的有效神经氨酸酶抑制剂的放射合成
2. Radiosynthesis of carbon 14 and tritium labeled potent neuraminidase inhibitors [J] . Raja, S., St George, Journal of Labelled Compounds and Radiopharmaceuticals . 2010,第5a6期

机译：碳14和氚标记有效神经氨酸酶抑制剂的可覆盖合成
3. Synthesis of deuterium-, tritium-, and carbon-14-labeled BILN2061, a potent hepatitis C virus protease inhibitor [J] . Bachir Lath, Matt Hrapchak, Vida Gorys, Journal of Labelled Compounds and Radiopharmaceuticals . 2005,第6期

机译：氘，tri和碳14标记的BILN2061（一种有效的丙型肝炎病毒蛋白酶抑制剂）的合成
4. SYNTHESIS OF S'-HYDROXY-L-TRYPTOPHAN LABELED WITH CARBON-14, DEUTERIUM AND TRITIUM [C] . Elzbieta Boroda, Marianna Kahska, Ryszard Kanski International Symposium on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds . 2004

机译：用碳-14，氘和氚标记的S'-羟基-L-色氨酸的合成
5. A QUANTITATIVE DETERMINATION OF CHITIN INTERMEDIATE POOLS DURING THE INCORPORATION OF CARBON-14 LABELED N-ACETYLGLUCOSAMINE AND TRITIUM LABELED GLUCOSE IN THE CRAYFISH, ORCONECTES SANBORNI. [D] . HETTICK, BRUCE PHILLIP. 1976

机译：在小龙虾或圆锥形虾中掺入碳14标记的N-乙酰葡萄糖胺和T标记的葡萄糖过程中甲壳素中间池的定量测定。
6. Tritium-Labeled Compounds II. General-Purpose Apparatus and Procedures for the Preparation Analysis and Use of Tritium Oxide and Tritium-Labeled Lithium Borohydride [O] . Horace S. Isbell, Joseph D. Moyer 1959

机译：t标记的化合物II。通用设备以及氧化和Tri标记的硼氢化锂的制备分析和使用程序
7. Corrigendum: Potent and selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 labeled with carbon-13 and carbon-14 [O] . Bachir Latli, Matt Hrapchak, Jolaine Savoie, 2018

机译：逆变：用碳-13和碳-14标记的11β-羟类脱氢酶1的有效和选择性抑制剂。

Radiosynthesis of carbon 14 and tritium labeled potent neuraminidase inhibitors

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